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Research and Reporting Methods Annals of Internal Medicine Net Reclassification Improvement: Computation, Interpretation,and ControversiesA Literature Review and Clinician's Guide Maarten J.G. Leening, MD, MSc; Moniek M. Vedder, MSc; Jacqueline C.M. Witteman, PhD; Michael J. Pencina, PhD;and Ewout W. Steyerberg, PhD The net reclassification improvement (NRI) is an increasingly pop-

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Indonesia (see also ) Abused domestic worker is homeAn Indonesian domestic worker, Ceriyati Dapin, 33, who fled from her abusive Malaysian employer, was reunited with her family on 22 June. Indonesian Foreign Ministry spokesman Kristiarto Legowo said that the government would facilitate her trip back to Malaysia to pursue her legal case. Malaysian police have arrested the employer and charged her with unlawful confinement and causing injury with a dangerous weapon. Following the incident, Indonesia and Malaysia have agreed to revise the MOU on migrant workers. Both countries will form a committee to revise the articles to ensure better working conditions for Indonesian workers in Malaysia. Indonesian Minister for Manpower and Transmigration Eman Suparno argued that the provision permitting employers to hold the passports of workers in the informal sector render workers vulnerable and increases their risk of detention during immigration raids. According to data from the Ministry of Manpower and Transmigration, Indonesia deployed some 3.9 million workers, with as many as 1.2 million going to Malaysia. Migrant workers should keep their passportsParticipants in a seminar on human trafficking, organized by the US Embassy, agreed that Indonesian workers abroad are abused because they do not have their passports with them. There are some 1.2 million regular and 500,000 irregular Indonesian workers in Malaysia. Endang Sulistyaningsih, director of promotion at the National Agency for the Placement and Protection of Indonesian Overseas Workers, said that the government asked the Malaysian government to permit Indonesian workers to keep their passports at a renegotiation of the bilateral MOU on migrant workers in Surabaya on 28 and 29 June. Also under discussion are a wage raise, a day off, and basic requirements employers should meet, such as no criminal record and a certain income level. Wahyu Susilo, founder of Migrant Care, said that Malaysia would not be able to meet Indonesia's demand for workers to keep their passports because Malaysia's law stipulates that employers must keep their workers' passport. Indonesians arrested in the USOn 19 June, US immigration authorities arrested 81 irregular immigrants – 76 Indonesians and four Malaysians – at Iridium Industries Inc., a plastics factory in Pennsylvania. Iridium's plant manager, Wayne Migliaccio, said his company uses several recruitment agencies and it is their responsibility to check workers' immigration status. The Indonesian government has demanded access to the Indonesian migrants 76 Indonesians to ensure that they get legal assistance, said a Foreign Ministry spokesman Kristiarto Legowo. The workers allegedly overstayed their visas. 3 Indonesians to be deportedThree irregular Indonesian workers, identified as Bambang Heri, Lestari Budiman and Hans Woworuntu, currently detained at the Lackawanna County detention center, Pennsylvania are to be deported. They arrived in the US in 2000 and were arrested in April this year. Another Indonesian, identified as Suratman, is still consulting his lawyer on whether he would accept deportation or try to extend his stay permit in the US. Indonesian in US detention drugged for deportationTwo immigrants, from Indonesia and Senegal, claiming they were forcibly drugged for deportation sued the US Department of Homeland Security. The American Civil Liberties Union of Southern California filed the suit, demanding a federal court prohibit authorities from drugging deportees taking commercial flights unless a physician prescribes it is necessary. Raymond Soeoth, a 38-year-old Indonesian, was given the drugs Haldol and Cogentin in December 2004 at a Los Angeles detention center. The organization filed the suit said he had no history of mental illness and was not examined by a doctor before being drugged. Deported migrants maltreated by authorities at home

Microsoft word - §+1+kartellverbot.doc

Prof. Dr. Christian Schubel Sommersemester 2008 Europäisches Wettbewerbsrecht § 1 Das Kartellverbot – Tatbestand und Rechtsfolgen I. Sachlicher und örtlicher Anwendungsbereich das europäische Kartellrecht gilt umfassend € es gibt also keine Bereichsausnahmen, insb. unterstehen auch Banken, Versicherungen und Versorgungsunternehmen dem europäischen Kartellrecht

svsu.edu2

An Altered Life Process: Colorectal Cancer Ashleigh VanBlarcom College of Health & Human Services Nominated by Mary Graiver, Department of Nursing Ashleigh Van Blarcom, in the Bachelor of Science in Nursing program, is from Saginaw and will graduate May 2011. She will be a nurse extern in the infusion center at MidMichigan Medical Center this summer. As a nurse, she plans to

Microsoft word - final report first stage.doc

Director: Prof. Samuel Pohoryles The Culture of Water Final Report of the First Stage The Andreas Agricultural Development Trust Founded 1997 by Mr. Dwayne O. Andreas, Archer Daniels Midland Co., Illinois, USA Phone: +972-3-5680680 y Fax: +972-3-5627265 y Email: s.pohoryles@peres-center.org The Peres Center for Peace, 2 HaShalom Rd., Tel Aviv, Israel 67892

silkworthlodge.co.uk

Jersey Alcohol Profile Health Intelligence Unit, November 2015 HIU INFORMATION READER Document purpose Report on Alcohol indicators for Jersey in 2015 Jersey Alcohol Profile 2015 Health Intelligence Unit Publication date 17 November 2015 States of Jersey Statistics Unit, States of Jersey Police, Social Circulation list Security, HSSD, Superintendent Registrar Biennial report on alcohol use and its consequences for Islanders in Jersey for 2015. Information on consumption and patterns of

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Gender Differences in Treatment Response to Sertraline Versus Imipramine in Chronic Depression Susan G. Kornstein, M.D. Objective: The authors examined gender study. Gender differences in time to re- differences in treatment response to ser- sponse were seen with imipramine, with Alan F. Schatzberg, M.D. traline, a selective serotonin reuptake in-

Independently extensible solutions to the expression problem

Independently Extensible Solutions to the Expression Problem Matthias Zenger, Martin Odersky École Polytechnique Fédérale de Lausanne 1015 Lausanne, Switzerland Technical Report IC/2004/33 challenge is now to find an implementation techniquewhich satisfies the following list of requirements: The expression problem is fundamental for the develop-ment of extensible software. Many (partial) solutions to

spitexniesen.ch

Informationen aus der Spitex Niesen Informationen aus der Spitex Niesen Informationen aus der Spitex Niesen Strategieworkshop vom Mittwoch, 8. Juni 2016 Tendenzen und Der Vorstand der Spitex und die Geschäftsleitung haben sich am Mittwoch 8. Juni 2016 zu einem Veränderungen Strategieworkshop getroffen. Ziel war erkennen. 

smctsm.org.mx

Superficies y Vacío 29 (1) 24-31, March 2016. © Sociedad Mexicana de Ciencia y Tecnología de Superficies y Materiales Síntesis de catalizadores basados en TiO2 modificado con Sn: Caracterización y evaluación de su desempeño fotocatalítico en la degradación de AINEs presentes en aguas residuales D.A. Solís-Casadosβ,*, A. Alcantara-Cobosγ

surf-1.org

What Is Prostate Cancer? The prostate The prostate is a gland found only in men. As shown in the picture below, the prostate is just below the bladder and in front of the rectum. It is about the size of a walnut. The tube that carries urine (the urethra) runs through the prostate. The prostate contains cells that make some of the fluid (semen) that protects and nourishes the sperm.

service.blackanddecker.it

Intended use f. If operating a power tool in a damp location is unavoidable, use a residual current device (RCD) Your Stanley Fat Max torch has been designed for providing protected supply. Use of an RCD reduces the risk of illumination. This tool is intended for professional and private, electric shock. non professional users.

s216270108.onlinehome.fr

Uncaria tomentosa Family: Rubiaceae Common Names: cat's claw, unha de gatoParts Used: Vine bark, root Description Cat's claw (U. tomentosa) is a large, woody vine that derives its name from hook-like thorns that grow along the vine and resemble the claws of a cat. Two closely related species of Uncaria are used almost interchangeably in the rainforests: U. tomentosa and U. guianensis. Both species

Arxiv:astro-ph/0303428v1 18 mar 2003

Measuring cosmology with Supernovae Saul Perlmutter1 and Brian P. Schmidt2 Physics Division, Lawrence Berkeley National Laboratory, University of California,Berkeley, CA 94720, USA Research School of Astronomy and Astrophysics, The Australian NationalUniversity, via Cotter Rd, Weston Creek, ACT 2611, Australia Abstract. Over the past decade, supernovae have emerged as some of the most power-ful tools for measuring extragalactic distances. A well developed physical understandingof type II supernovae allow them to be used to measure distances independent of theextragalactic distance scale. Type Ia supernovae are empirical tools whose precision andintrinsic brightness make them sensitive probes of the cosmological expansion. Bothtypes of supernovae are consistent with a Hubble Constant within ∼10% of H0 = 70

staffdcs.shef.ac.uk

Evaluating Semantic Search Query Approaches with Expert and Casual Users Khadija Elbedweihy, Stuart N. Wrigley, and Fabio Ciravegna Department of Computer Science, University of Sheffield, UK Abstract. Usability and user satisfaction are of paramount importancewhen designing interactive software solutions. Furthermore, the optimaldesign can be dependent not only on the task but also on the type ofuser. Evaluations can shed light on these issues; however, very few stud-ies have focused on assessing the usability of semantic search systems.As semantic search becomes mainstream, there is growing need for stan-dardised, comprehensive evaluation frameworks. In this study, we assessthe usability and user satisfaction of different semantic search query in-put approaches (natural language and view-based) from the perspectiveof different user types (experts and casuals). Contrary to previous stud-ies, we found that casual users preferred the form-based query approachwhereas expert users found the graph-based to be the most intuitive.Additionally, the controlled-language model offered the most support forcasual users but was perceived as restrictive by experts, thus limitingtheir ability to express their information needs.

Abstract

Nankai University May 21, 2010 7:00-8:00 Tom Rapoport "How the ER gets into shape" May 22, 2010 Proteins in generating membrane vehicles I 8:00-8:40 Harvey McMahon "Sculpting Cell Membranes: Understanding pathways of endocytosis and exocytosis" 8:40-9:20 Pietro De Camilli "Bending membranes at sites of endocytosis"

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Brasilien 2008 Exkursionsbericht der Stahlbauer 1. Einleitung Unsere Exkursion hat uns rund 10.000 km weit weg auf die Südhalbkugel der Erde geführt. Brasilien ist ein riesiges Land, wir haben nur einen kleinen Teil bereist und ein wenig kennen gelernt. Selbst in diesem klei-nen Teil sind die Entfernungen so groß, dass wir über Nacht in recht komfortablen Reisebussen bzw. mit dem Flugzeug gereist sind.

sismo24.cl

SIMULACIÓN DEL TSUNAMI DE 1960 EN UN ESTUARIO DEL CENTRO-SUR DE CHILE Revista de Geografía Norte Grande, 33: 5-18 (2005) Simulación del tsunami de 1960 en un estuario del centro-sur de Chile1 MARCELO LAGOS2, DANTE GUTIÉRREZ3 Se modela el tsunami de 1960 en un estuario del centro-sur de Chile. Lareconstrucción del evento se realizó mediante la modelación del escenariosísmico tsunamigénico, utilizando una técnica de simulación numérica detsunamis de campo cercano, permitiendo caracterizar el proceso de gene-ración, propagación e inundación generada por las ondas en las áreascosteras bajas. Los resultados de la simulación del tsunami se validan conantecedentes y evidencias existentes del evento real.

Alzherimerwatch2015.fm

GUIDELINE WATCH (OCTOBER 2014): PRACTICE GUIDELINE FOR THE TREATMENT OF PATIENTS WITH ALZHEIMER'S DISEASE AND OTHER DEMENTIAS Peter V. Rabins, M.D., M.P.H.Barry W. Rovner, M.D.Teresa Rummans, M.D.Lon S. Schneider, M.D.Pierre N. Tariot, M.D. During development and approval of this guideline watch, from July 2012 to September 2014, Dr. Rabins reports providing legaltestimony for Janssen Pharmaceutica, Dr. Rovner reports serving as a consultant to GE Healthcare, and Dr. Rummans reports thatshe has nothing to disclose. From 3 years before development was initiated in July 2012 through September 2014, Dr. Schneider andthe University of Southern California received research or other grants from Abbott Laboratories, AstraZeneca, Baxter, Forest Phar-maceuticals, Inc., Forum, Genentech, Johnson & Johnson, Eli Lilly and Company, Lundbeck, Merck, Myriad, Novartis, Pfizer,Roche, and TauRx, Ltd. and from NIH (USC ADRC, ADCS, ADNI, Banner Alzheimer's Initiative, CitAD, phytoSERMs, Alzheim-er's disease trial simulations, allopregnanolone, P50 AG05142, R01 AG033288, R01 AG037561, UF1 AG046148), and the state ofCalifornia (California Alzheimer's Disease Program, California Institute for Regenerative Medicine). During that same time period,Dr. Schneider served as a consultant or on advisory panels for Abbott Laboratories, Abbvie, AC Immune, Accera, Allon, AstraZeneca,Avraham Pharmaceuticals, Ltd., Biogen Idec, Cerespir, Forest Pharmaceuticals, Inc., Forum, GSK, Johnson & Johnson, Eli Lilly andCompany, Lundbeck, Merck, Novartis, Orion, Roche, Servier, Stemedica, Ltd., Takeda, Targacept, TauRx, Toyama/FujiFilm, andZinfandel. In addition, Dr. Schneider serves on the editorial boards of Alzheimer's and Dementia: Translational Research and ClinicalIntervention (editor-in-chief), The Lancet Neurology (editorial board), Cochrane Collaboration (editor base), BMC Psychiatry (section ed-itor), Alzheimer's & Dementia (senior associate editor), Current Alzheimer Research (associate editor), Clinical Neuropharmacology (edi-torial board) and on the guidelines committee for the World Federation of Societies of Biological Psychiatry; served as an expert wit-ness or consultant on federal and state cases for plaintiffs against Lilly, Johnson & Johnson, and Pfizer and for defendants AstraZenecaand Pfizer; and has consulted with the state of California Department of Justice. During development and approval of this guidelinewatch, Dr. Tariot reports receiving consulting fees from Abbott Laboratories, AbbVie, AC Immune, Adamas, Avanir, Avid, Boehringer-Ingelheim, Bristol Myers Squibb, California Pacific Medical Center, Chase Pharmaceuticals, Chiesi, CME, Inc., Cognoptix, Elan,Eli Lilly, GlaxoSmithKline, Janssen, Medavante, Medivation, Merck and Company, Merz, Otsuka, Roche, and Sanofi-Aventis. Dr.Tariot reports receiving research support from AstraZeneca, Avanir, Avid, Baxter Healthcare Corp., Bristol Myers Squibb, Cognop-tix, Eli Lilly, Functional Neuromodulation (f(nm)), GE, Genentech, GlaxoSmithKline, Janssen, Medivation, Merck and Company,Pfizer, Roche, Targacept, and Toyama as well as the National Institute on Aging and the Arizona Department of Health Services. Dr.Tariot also reports stock options in Adamas and that he is listed as a contributor to a patent owned by the University of Rochester,"Biomarkers of Alzheimer's Disease."

ss-pub.org

"Science Stays True Here" Biological and Chemical Research, Volume 2015, 241-257 Science Signpost Publishing Natural Coumarins: QSTR Approaches Regarding Their Genotoxicity Estela Guardado Yordi1,2,*, Maria João Matos2, Lourdes Santana2, Eugenio Uriarte2, Orlando Abreu1 and Enrique Molina Pérez2,3 1. Departamento de Ciencia y Tecnología de los Alimentos, Universidad de Camagüey "Ignacio Agramonte Loynaz", Circunvalación Norte Km 5 ½, 7200, Camagüey, Cuba. 2. Departamento de Química Orgánica, Universidad de Santiago de Compostela, Facultad de Farmacia, Campus Vida, 15782, Santiago de Compostela, España. 3. Departamento de Química, Universidad de Camagüey "Ignacio Agramonte Loynaz", Circunvalación Norte Km 5 ½, 7200, Camagüey, Cuba. Received: May 26, 2015 / Accepted: June 29, 2015 / Published: August 25, 2015 Abstract: Coumarins are a group of phytochemicals with multiple applications in different fields, such as food and medicine. Many of their benefits are based on the different activities that they display, within which stand antioxidant properties. However, some conflicting evidences suggest the need to clarify or estimate the safety aspects and genotoxicity of this group of compounds. In this sense it has been shown in previous studies that some of them have presented pro-oxidant activity in vitro and clastogenic activity in silico. Therefore, in this paper chemical structures of coumarins that come from several natural sources were studied. These coumarins belong to the chemical subclasses: simple coumarins, furocoumarins, dihydrofurocoumarins, pyranocoumarins, phenylcoumarins and biscoumarins. Thepre-selected database was formed taking into account topological-structural information, using molecular descriptors from the TOPSMODE approach. A virtual screening, that used a structure-clastogenic activity model and linear discriminant analysis (LDA) technique, was also performed. Several natural coumarins showed clastogenic activity in silico. For this family, the QSTR associated the probability of being active to the presence of hydroxy and methoxy groups in the molecules. It is of positive contribution of the fragment that forms the bay region of the pyranocoumarinic system. These in silico results may contribute to the safe design of new foods, nutraceuticals or drugs. It may also be important in the prevention of cancer, in which pathology these substances show pro-oxidant activity. Keywords: Coumarins, clastogenic activity, pro-oxidant activity, TOPSMODE approach.

sourcedb.igg.cas.cn

International Geology Review, Vol. 49, 2007, p. 374–388. Copyright © 2007 by V. H. Winston & Son, Inc. All rights reserved. Review of the Lithium Isotope System as a Geochemical Tracer YAN-JIE TANG,1 HONG-FU ZHANG, AND JI-FENG YING State Key Laboratory of Lithospheric Evolution, Institute of Geology and Geophysics, Chinese Academy of Sciences,

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on depression ISSUE 2, 2015 framıngham on allergy Michael Bauer, MD PhD framıngham on anaesthesiology Professor of Psychiatry, Director of the department of framıngham on atherosclerosis Psychiatry and Psychotherapy, framıngham on breast cancer University Hospital Carl Gustav Dick J. Veltman, MD PhD framıngham on colorectal cancer

stanfordhealthcare.org

SCHEDULING CENTER  PHONE: (650) 723-6855  FAX: (650) 723-6036 HOSPITAL – 300 Pasteur Drive BLAKE WILBUR OUTPATIENT CLINIC – 900 Blake Wilbur Drive ADVANCE D MEDICINE CENTER/CANCER CENTER – 875 Blake Wilbur Drive STANFORD MEDICINE IMAGING CENTER – 451 Sherman Avenue, Palo Alto STANFORD MEDICINE OUTPATIENT CENTER – 450 Broadway, Redwood City