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PMMC: Psychotropic Medication Monitoring Checklists Disclaimer
The authors do not intend that the PPMC should be used in lieu of comprehensive, appropriate care. Every reasonable effort has been made to ensure that the information provided in the PMMC is accurate and up to date. The potential side effects listed in the PMMC should be reviewed against current information relevant to each medication. The physician or prescriber should ensure through comprehensive assessment that medication is appropriate for the individual child before prescribing. Health professionals are responsible for providing appropriate clinical oversight and care subject to the professional practice regulations where the child receives care. Caregivers should tell their child's doctor about all potential side effects that the child experiences. Some of the side effects on the PMMC require urgent medical attention, and these are indicated with the words "NOTIFY MEDICAL". If the caregiver is unsure whether urgent medical attention is needed for a side effect that the child is experiencing, the caregiver should contact the child's appropriate health professional for advice. Table of Contents Note to Physicians.3 Note to Caregivers.4 Brief Definitions of Potential Side Effects.6 Alpha Agonists.9 Anticonvulsants.10 Antipsychotics.11 Note to Physicians Purpose of the PMMC
The PMMC are used to track potential side effects that children may experience from psychotropic medication. These tools were designed to streamline the documentation and communication of potential side effects associated with the paediatric use of psychotropic medications. As you know, psychotropic medications have been used increasingly over the last few decades with children without comprehensive knowledge of safety, risks and adverse effects. This significantly amplifies the need to vigilantly monitor for such concerns. Tracking symptoms and interpreting the likelihood of side effects can be useful in directing and monitoring treatment, as well as preventing serious and seminal events related to medication use. Use of the PMMC has been demonstrated to improve various elements of side effect monitoring for children in residential care. For more details see: Ninan, A., Stewart, S. L., Theall, L., King, G., Evans, R., Baiden, P., & Brown, A. (2014). Psychotropic medication monitoring checklists: Use and utility for children in residential care. Journal of the Canadian Academy of Child and Adolescent Psychiatry, 23(1), 38-47. Completing the PMMC
Each PMMC accommodates a full week of daily side effect monitoring. Supply the family with copies of the PMMC relevant to which medication is prescribed. The caregiver (or other responsible individual) is to indicate if a potential side effect was observed in the course of each day with a check mark . A "Baseline" column is also included for the caregiver to indicate if a potential side effect was present before beginning the medication. The next page provides notes for caregivers on using the PMMC. The PMMC as a Tool in Comprehensive Clinical Care
Side effects listed on the PMMC are separated into the categories: Common, Infrequent, and Rare But
Serious. Some of the side effect symptoms listed as common and infrequent may also pose a serious risk
to the child. When providing the PMMC to the family, you may wish to review the potential side effects with the caregiver and child, and instruct on which symptoms represent an urgent concern requiring immediate medical attention, and which potential side effects can be communicated to you in the course of regular follow up appointments if observed. Note to Caregivers What is the PMMC?
The PMMC are sheets that list possible side effects that children might experience when taking certain types of medication. The PMMC are a tool to help you to be aware of what possible side effects to watch for in your child. The PMMC are also a way for you to document observed side effects to help you communicate these to your child's doctor. The possible side effects are organized into 3 sections on each PMMC according to how likely each are to occur: Common, Infrequent, and Rare But Serious. It is important to keep in mind that even some of the side effects in the Common and Infrequent sections might be a serious medical concern for your child requiring urgent care. Talk to your child's doctor to find out which potential side effects would require an emergency response. How do I use the PMMC?
Make side effect monitoring part of your daily routine. For example, at the end of each day read the list of potential side effects and think about if you noticed any that day with your child. You can also talk to your child about how he/she is feeling, and get other family members involved in monitoring as well.  Use each PMMC sheet for a full week of monitoring for side effects. In the spaces provided at the top of the sheet, write the child's name, prescriber's name, and the date that the week  Place a check mark next to the name of each medication that your child is taking that week and record the dosage.  There is a column labeled "Baseline" on each PMMC. If your child had one or more of the symptoms listed on the PMMC before beginning the medication then place a check mark in the Baseline column for the row that corresponds with the side effect symptom.  When you notice a possible side effect, place a check mark in the space that corresponds to the row for the potential side effect you observed and column for the day(s) of the week that your child experienced it.  Each day, be sure to check the last two rows on each sheet: o Check for each day that medication was administered o Check for each day if NO side effects observed  There is space at the bottom of each PMMC for your comments. You can write in this space any questions or concerns you have to help you remember when you talk to your child's doctor. You can also write here if you think there may be another reason for the observed side effect symptom that is not related to medication (for example, the child had contact with poison ivy and that may be the cause of the observed rash). What should I do if my child has one of the side effects listed?
You should tell your child's doctor about all potential side effects that your child experiences. Some of the side effects on the PMMC require urgent medical attention, and these are indicated with the words "NOTIFY MEDICAL". Your child's doctor may tell you if other potential side effects listed would also require urgent medical attention for your child. Side effects that do not require an urgent medical response can be communicated to the doctor during a regular follow up appointment. If you are unsure whether urgent medical attention is needed for a side effect that your child is experiencing, contact your child's doctor to ask. Brief Definitions of Potential Side Effects1 Abnormal Eye Movements: Side to side, up and down or rotatory movements of eyes, or both eyes looking in different directions. Abdominal Pain: Lower belly ache. Agitation: Confused, restless and excited, extreme emotional disturbance, extreme worry or anxiety that is reflected in someone's behaviour, movements or voice. Appetite Change: Change in desire to eat food. Appetite Decrease: Less interest in eating food. Appetite Loss: No desire to eat food. Bedwetting: Urination at night in bed. Blurred Vision: Not seeing sharp outlines clearly, hazy appearance. Bruising: Areas of reddish purple discolouration of skin. Chest Pain: Discomfort in the chest. Clumsy: Poor balance and coordination, accident prone. Confusion: Inability to think clearly. Constipation: When bowel movements occur less often than usual or consist of hard, dry stools that are painful or difficult to pass. Although bowel habits vary, 3 or less bowel movements a week may be an indicator of constipation. Depressed Affect: Feeling low or down. Diarrhea: Increase frequency or unusual frequency of bowel movements and/or decreased consistency/increased liquidity or looseness of stools. Dizziness: Light-headedness. Drooling: Excessive salivation. Drowsiness: Difficulty staying awake. Dry Eyes: Decreased tears. Dry Mouth: Decreased saliva in mouth. Dry Nose: Decreased mucus in nose, possibly with nose bleeding. Dry Skin: Decreased skin moisture and itchiness. Easy Bruising: Prone to reddish purple discolouration of skin with minimal pressure on the skin. Euphoria: Exaggerated, unrealistic and intense feeling of well-being or happiness. Excessive Sweating: Increased perspiration or wet skin. Eye Pain: Burning, throbbing, aching or stabbing sensation in or around the eye. 1 Definitions based on souin combination with pharmacist and physician input. Fast Heart Rate / Heart Palpitations: Feeling the heart is racing. Feeling Cold: Feeling an uncomfortable lack of warmth, may include shivering or chills. Fever: High temperature or very warm body. Focusing Problems: Difficulty concentrating or paying attention. Hair Loss: Hair falling out. Hallucinations: Seeing, hearing, smelling, tasting or feeling things that do not exist. Headache: Pain in head. Heart Burn: Painful burning in chest or throat. Inability to Breathe or Swallow: Choking or gagging sensation. Insomnia: Trouble falling or staying sleep. Irregular Pulse Rate: Variation in heart rate and rhythm. Irritability: More excitable or bad tempered than normal. Lack of Movement: Being still or stiff. Metallic Taste: Abnormal salty or rancid taste in mouth. Mood Swings: Extreme and rapid highs and lows in mood. Mouth Ulcers: Canker sores in mouth. Muscle Stiffness: Muscle tightness or soreness. Nausea: Uneasiness in the stomach with urge to vomit. Nervousness: Apprehensiveness in conjunction with being scared and/or highly excitable. Rash or Hives: Welts or flat-topped bumps. Restless: Always in motion, not calm. Sedation: The bringing about of calmness, of mental and physical relaxation. Seizures: Convulsion or part of the body shaking rapidly and uncontrollably, or losing the ability to control a part of the body temporarily. Serotonin Syndrome: A group of symptoms caused by too much serotonin in the body, can be extremely serious. Symptoms include at least some of the following: Agitation, confusion, sweating, dilated pupils rapid heart rate, shivering, tremor, eyelid spasms, muscle twitches, muscle stiffness. Severe Rash: Change in colour or texture of a large area of skin generally with itching. Skin – Itchy: Sensation of feeling the need to scratch skin, with or without a visible rash. Skin Rash: Change in colour or texture of skin generally with itching. Sleep Disturbance: Over arousal or increased sleepiness. Sleepiness: Feeling the need for sleep. Slowed Movements: Sluggish or lethargic. Slurred Speech: Decreased clarity of spoken words. Sore Throat: Painful redness of the throat. Stiffness of Tongue: Weakness in the tongue or feeling unable to move the tongue. Stomach Pain: Upper belly ache. Sudden Stiffness: Rigidity or decreased flexibility. Suicidal Ideation: Having thoughts and/or intent to kill oneself. Sustained Involuntary Muscle Contraction: Spasm. Swelling: Enlargement or increase in size of an area. Swelling – General: Widespread swelling of the body. Thirsty: Cravings for fluids. Tics: Sudden repetitive movement of an area of the body. Tingling in Fingers or Toes: Tickling or pricking sensation in fingers or toes. Tiredness: Fatigue, exhaustion, feeling depleted of strength and/or energy. Tremor: Trembling or quivering. Twitching: Jerky or spasmodic movement. Unable to Sit Still: On the move always. Unsteady: Unable to firmly remain upright. Unsteady Gait: Abnormal walk. Urination – Burning: Pain while urinating. Urination – Frequent: Need to pass urine more than usual. Urinating Trouble: Dribbling, or difficulty starting urination and weak urine stream. Urine Dark or Feces Pale: Change in colour of urine or feces. Vomiting: Throwing up or puking. Weight Gain: Increase in body weight. Weakness: Lack of strength. Worsened Suicidal Ideation: An increased preoccupation of killing oneself that has become more regular Yellow Skin/ Eyes: Jaundice, changing colour of the skin or whites of the eyes. Psychotropic Medication Monitoring Checklist (PMMC) ALPHA AGONISTS
Week Start Date: CLONIDINE (CATAPRES) given this week and GUANFACINE XR (INTUNIV) record dosage:

Instructions:
Place a check mark in the correct space for observed side effects. To indicate days when no
monitoring took place (i.e., child was away) place a line down the length of the column(s).
BASELINE MON TUE WED THUR FRI SAT SUN INFREQUENT:
BASELINE MON TUES WED THUR FRI SAT SUN RARE BUT SERIOUS (NOTIFY MEDICAL):
BASELINE MON TUES WED THUR FRI SAT SUN Check for each day that medication was administered:
Check for each day if NO side effects observed:
CPRI (Home Version 2014) CSW or Medical Initials: _ Date: _ Psychotropic Medication Monitoring Checklist (PMMC) ANTICONVULSANTS
Week Start Date: CARBAMAZEPINE (TEGRETOL) LAMOTRIGINE (LAMICTAL) given this week and DIVALPROEX (EPIVAL) TOPIRAMATE (TOPAMAX) record dosage:

Instructions:
Place a check mark in the correct space for observed side effects. To indicate days when no
monitoring took place (i.e., child was away) place a line down the length of the column(s).
BASELINE MON TUE WED THUR FRI SAT SUN Abnormal Eye Movements Focusing Problems INFREQUENT:
BASELINE MON TUES WED THUR FRI SAT SUN Depressed Affect Rash or hives (NOTIFY MEDICAL) Tingling in Fingers or Toes Urination - Burning Urination - Frequent Urine Dark or Feces Pale RARE BUT SERIOUS (NOTIFY MEDICAL):
BASELINE MON TUES WED THUR FRI SAT SUN Yellow Skin/ Eyes Check for each day that medication was administered:
Check for each day if NO side effects observed:
COMMENTS (continue on back of page if needed): CPRI (Home Version 2014) CSW or Medical Initials: _ Date: _ Psychotropic Medication Monitoring Checklist (PMMC) ANTIPSYCHOTICS
Week Start Date: ARIPIPRAZOLE (ABILIFY) OLANZAPINE (ZYPREXA) ASENAPINE (SAPHRIS) QUETIAPINE (SEROQUEL) given this week and CHLORPROMAZINE (LARGACTIL) RISPERIDONE (RISPERDAL) HALOPERIDOL (HALDOL) ZIPRASIDONE (ZELDOX)
Instructions:
Place a check mark in the correct space for observed side effects. To indicate days when no
monitoring took place (i.e., child was away) place a line down the length of the column(s).
BASELINE MON TUE WED THUR FRI SAT SUN Muscle Stiffness Sleepiness/ Tiredness Tremors/ Slowed Movements Unable to Sit Still Urinating Trouble RARE BUT SERIOUS (NOTIFY MEDICAL):
Extreme stiffness or lack of movement, very high fever, mental confusion, irregular pulse
rate, eye pain (EMERGENCY RESPONSE)
Fever, sore throat, yellowing of eyes/skin,
easy bruising Seizure Stiffness of Tongue Sustained involuntary muscle contraction Sudden stiffness and inability to breathe or swallow (EMERGENCY RESPONSE)
Check for each day that medication was administered:
Check for each day if NO side effects observed:
CPRI (Home Version 2014) CSW or Medical Initials: _ Date: _ Psychotropic Medication Monitoring Checklist (PMMC) ATOMOXETINE (STRATTERA)
Week Start Date: ATOMOXETINE (STRATTERA) given this week and **Contraindicated in Glaucoma** record dosage:

Instructions:
Place a check mark in the correct space for observed side effects. To indicate days when no
monitoring took place (i.e., child was away) place a line down the length of the column(s).
BASELINE MON TUE WED THUR FRI SAT SUN INFREQUENT:
BASELINE MON TUES WED THUR FRI SAT SUN RARE BUT SERIOUS (NOTIFY MEDICAL):
BASELINE MON TUES WED THUR FRI SAT SUN Jaundice (Yellow Skin or Eyes) Suicidal Ideation Check for each day that medication was administered:
Check for each day if NO side effects observed:
CPRI (Home Version 2014) CSW or Medical Initials: _ Date: _ Psychotropic Medication Monitoring Checklist (PMMC) LITHIUM
Week Start Date: given this week and (LITHANE, CARBOLITH, APO-LITHIUM, PMS-LITHIUM, DURALITH, LITHMAX) record dosage:

Instructions:
Place a check mark in the correct space for observed side effects. To indicate days when no
monitoring took place (i.e., child was away) place a line down the length of the column(s).
BASELINE MON TUE WED THUR FRI SAT SUN Urination - Frequent INFREQUENT:
BASELINE MON TUES WED THUR FRI SAT SUN Swelling - General Sleepiness or Tiredness Tingling in Fingers/ Toes RARE BUT SERIOUS (NOTIFY MEDICAL):
Check for each day that medication was administered:
Check for each day if NO side effects observed:
CPRI (Home Version 2014) CSW or Medical Initials: _ Date: _ Psychotropic Medication Monitoring Checklist (PMMC) SSRI - SELECTIVE
SEROTONIN REUPTAKE INHIBITORS
Week Start Date: CITALOPRAM (CELEXA) FLUVOXAMINE (LUVOX) given this week and ESCITALOPRAM (CIPRALEX) PAROXETINE (PAXIL) FLUOXETINE (PROZAC) SERTRALINE (ZOLOFT)
Instructions:
Place a check mark in the correct space for observed side effects. To indicate days when no
monitoring took place (i.e., child was away) place a line down the length of the column(s).
BASELINE MON TUE WED THUR FRI SAT SUN Dry Mouth / Eyes / Nose Sleepiness / Tiredness INFREQUENT:
Excessive Sweating Urination Trouble RARE BUT SERIOUS (NOTIFY MEDICAL):
BASELINE MON TUES WED THUR FRI SAT SUN Symptoms of Serotonin Syndrome: Confusion, Sweating, Seizure, Agitation, Diarrhea, Tremors, Chest Pain Worsened Suicidal Ideation Check for each day that medication was administered:
Check for each day if NO side effects observed:
CPRI (Home Version 2014) CSW or Medical Initials: _ Date: _ Psychotropic Medication Monitoring Checklist (PMMC) STIMULANTS
Week Start Date: METHYLPHENIDATE: given this week and DEXTROAMPHETAMINE + AMPHETAMINE: LISDEXAMFETAMINE:
Instructions:
Place a check mark in the correct space for observed side effects. To indicate days when no
monitoring took place (i.e., child was away) place a line down the length of the column(s).
BASELINE MON TUE WED THUR FRI SAT SUN Appetite Decrease Sleep Disturbance INFREQUENT:
BASELINE MON TUES WED THUR FRI SAT SUN Fast Heart Rate / Heart Palpitations RARE BUT SERIOUS (NOTIFY MEDICAL):
BASELINE MON TUES WED THUR FRI SAT SUN Check for each day that medication was administered:
Check for each day if NO side effects observed:
CPRI (Home Version 2014) CSW or Medical Initials: _ Date: _

  • PMMC User Manual -20-Jun-2014
  • PMMC home manual -20-Jun-2014 - clean
  • Source: http://cpri.ca/index.php/download_file/965/668/

    Non-digestible carbohydrates and glycaemic control

    NON-DIGESTIBLE CARBOHYDRATES AND GLYCAEMIC CONTROL G. Livesey Independent Nutrition Logic Ltd (UK), 21 Bellrope Lane, Wymondham, Norfolk, NR18 OQX, United Kingdom. Tel: +44-1953-60-6689. Fax: +44-1953-60-0218. E-mail: [email protected] ABSTRACT Mechanisms are indicated whereby fibre and polyols could reduce blood glucose and insulin concentrations and so potentially help to reduce the prevalence of diabetes, CHD, and certain cancers. Seven are identified independent of associated substances or antioxidant or lignans. Further, high cereal fibre intake additionally lowers the starch:fibre ratio thus lowering the glycaemic index of total carbohydrate; this may be helped by fiber as cell walls in whole grain causing some starch to be unavailable. It seems that glycaemic index expressed as g equivalents per g available carbohydrate does not account for the full effects of non-digestible carbohydrates on lowering of blood glucose in some circumstances, whereas glycaemic load in units of g glucose equivalents per day (or per unit food) would. Overall, the glycaemic load appears stronger at present than glycaemic index in several circumstances: the epidemiology on development of type-2 diabetes and heart disease when combined from different studies; the epidemiology of HDL, TG, and C-reactive protein; the epidemiology of haemorrhagic stroke; the interventions on body weight in ad-libitum studies; and the interventions on glycated proteins and fasting blood glucose in diabetics. Information appears more consistent than is generally discussed in the literature and appears independent of the concepts of whole grain and reduced energy density. Scope exists for a reduction in glycaemic load by replacing high glycaemic available carbohydrate with either low-glycaemic available carbohydrate or fibre or polyols and this potentially could reduce the prevalence of diabetes and CHD by up to thirty percent.

    Microsoft word - portada3.doc

    PROYECTO BÁSICO Y DE EJECUCIÓN _ OCTUBRE 2.012: ACABADOS INTERIORES del SALÓN DE ACTOS del CENTRO CULTURAL - AULAS DE DANZA Y MÚSICA. CALLE PASADA nos 11 y 13. SOTILLO DE LA ADRADA. ÁVILA PROPIEDAD: EXCMO. AYUNTAMIENTO DE SOTILLO DE LA ADRADA 1. MEMORIA DESCRIPTIVA 2. MEMORIA CONSTRUCTIVA 3. HOJAS JUSTIFICATIVAS CTE 4. DOCUMENTACIÓN FOTOGRÁFICA 5. DOCUMENTACIÓN CATASTRAL 6. PLANING DE OBRA 7. PLAN DE CONTROL 8. PLIEGO DE CONDICIONES 9. DOCUMENTACIÓN GRÁFICA 10. ESTUDIO BÁSICO DE SEGURIDAD Y SALUD AM. ANEJO A LA MEMORIA. MEMORIA ADMINISTRATIVA P. MEDICIONES Y PRESUPUESTO