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Apc.iisc.ernet.in
with the indian institute of science
Department of
Mathematics
Early Research
Volume 3 • Issue 2
Connect Volume 3 • Issue 2
Sudhi Oberoi is a Project Trainee at the Archives and
Vrushal Pendharkar is a freelance science writer
Publications Cell
Debadrita Paria is a PhD student at the Centre for Nano
Subhayan Sahu is an undergraduate student
Science and Engineering
Megha Prakash is a Consultant Editor at the Archives
Taru Verma is a PhD student in the Department of
and Publications Cell
Nithyanand Rao is a Consultant Editor at the Archives
Syama Sreedharan is a PhD student in the Department of
and Publications Cell
Karthik Ramaswamy is the Editor, CONNECT, at the
Ellen Brock is a consultant in data analytics
Archives and Publications Cell
Cressida Hamlet is a Master's student at the Department
Manbeena Chawla is a Research Associate at the Centre
of Computer Science and Automation
for Infectious Disease Research
Prateeksha Varshney is a Master's student at the
Science Media Center is a joint initiative of IISc and
Department of Computational and Data Sciences
Saleem Ahmed is a Senior Research Fellow at the Centre
Manu Rajan is a Technical Officer at the Archives and
for Product Design and Manufacturing
Publications Cell
Aditi Jayaram is a Project Assistant at the Centre for
Ranjini Raghunath is a Development Officer at the
Ecological Sciences
Office of Development and Alumni affairs
Anupam Purwar is a Visiting Scientist at the Materials
Navin S is a Master's student in the Department of
Electrical Engineering
Front Cover:
Back Cover:
Front Inside
Back Inside Cover:
Cover: Foliage (IISc
Photography Club)
CONNECT TEAM
Karthik Ramaswamy (Editor, CONNECT, Archives and Publications Cell)
Megha Prakash (Consultant Editor, Archives and Publications Cell)
Nithyanand Rao (Consultant Editor, Archives and Publications Cell)
Sudhi Oberoi (Project Trainee, Archives and Publications Cell)
Manu Rajan (Technical Officer, Archives and Publications Cell)
TA Abinandanan (Chairperson, Archives and Publications Cell & Department of Materials Engineering)
Photography: IISc Photography Club (unless otherwise mentioned)
Email: [email protected]
Phone: 91-080-2293 2066
Address: Archives and Publications Cell
Indian Institute of Science, Bangalore 560 012, India
Connect Volume 3 • Issue 2
fROM ThE CONNECT TEAM
Until the advent of vinyl in the 1950s, gramophone records were made from shellac—the processed form of lac—a resinous substance produced by a group of sap-sucking insects. In India, lac has been harvested for centuries, but its economic importance surged in the early 20th century when its versatility became evident to British industry. Soon lac was a sought-after raw material. And like many other raw materials that powered Britain's industrial might, this too had to be sourced from its colonies, particularly India, the principal producer of lac in the world.
Realizing the importance of lac research, the British government tapped into the existing expertise in chemistry in the Indian Institute of Science ('IISc' or 'Institute' from here on) to study lac and its products. And new researchers, including biologists, were hired to investigate this prized commodity. The story of lac research in IISc has been pieced together by Megha Prakash and Manu Rajan in this issue.
Also in this issue, Nithyanand Rao throws light on the Department of Mathematics at IISc. Conventionally, mathematics has been divided into pure and applied mathematics. They even have their own scholarly societies. However, this distinction is often superficial. Many fields of pure mathematics had their origins in solving practical problems. And pure mathematics keeps finding new applications. For instance, number theory ("Thank God that number theory is unsullied by any application," the American mathematician, Leonard Eugene Dickson, is supposed to have said) is today integral to cryptography and encryption.
When it was established in 1956, the Department of Mathematics at IISc was called the Department of Applied Mathematics. But over the years, it has freed itself from the shackles of having to do research mainly to support science and engineering studies in the Institute. As its current Chair, Gadadhar Misra, says, "…we live happily without having any biases about what sort of mathematics should be done."
In March this year, IISc celebrated its Open Day. We have a report from the ground by Sudhi Oberoi, who tells us about the activities that were on display at this year's event, fast becoming the Institute's most important outreach initiative. She also informs us about what goes into planning for an event of this magnitude.
This issue has much more for the reader to reflect on, including insights into journalism, provided by veteran broadcaster, Mark Tully, in an interview with Nithyanand Rao and Karthik Ramaswamy.
Connect Volume 3 • Issue 2
In This Issue.
12 n Visitors
ON CAMPUS
Guests of the Institute open up
DISPATChES fROM ThE
Meet researchers who are
SCIENCE fOR ALL
Reaching out to society
fULfILLING ThE PROMISE
28 @ In focus
Undergraduate students leave
the nest to start new lives
DEPARTMENT Of
hOT Off ThE PRESS
BRIDGING ThE SCIENCES
Top science stories from IISc
Connecting disciplines with a
Connect Volume 3 • Issue 2
36 J Events
CAMPUS ChRONICLES
News from various events on
A rendezvous with new
researchers at the Institute
AND ThE AWARD GOES
TO…
Institute denizens who won
recognition for their research
IN ThE NEWS
WAXING AND WANING
Of LAC RESEARCh
News related to IISc
Lectures
History of research into a
LOOK WhO'S TALKING
Faculty colloquiua
Connect Volume 3 • Issue 2
IISc's annual outreach event—Open Day—showcases cutting edge research in the Institute
and educates visitors about fundamental concepts in science and engineering
Using an optical illusion to demonstrate how the brain perceives the size of an object
SUDHI OBEROI
"I love mathematics," an excited Anamika Dubey
teachers, parents, science enthusiasts, media
declares as she attempts to solve a puzzle in a
personnel and more. They participated in
classroom in the Department of Mathematics
scientific demonstrations, talks, seminars,
at IISc. The fourth standard student from
movie screenings, discussions, and other
Kendriya Vidyalaya – AFS Yelahanka, who wants
activities organized as part of the event. The
to become a police officer when she grows up,
many food joints that were specially set up
was on campus with her father on the occasion
on the occasion were an added attraction.
of IISc's annual Open Day on 5 March this year.
According to the Public Relations Officer (PRO) of IISc, N Krishnamurthy, around 20,000 people
Anamika was one of the thousands of visitors
visited the Institute on Open Day this year, a
who thronged the campus on this day, along
jump of more than 50 percent compared to
with other school and college students,
Connect Volume 3 • Issue 2
Open Day is organized to showcase research
in the Institute and communicate important
The task of organizing this event rests on the
concepts in science and engineering to the
broad shoulders of an Open Day Committee,
general public. Its origins can be traced to a report
comprising all the Divisional Chairs, the PRO
of a Review Committee headed by JC Ghosh,
and Chairpersons of all the departments.
a former Director of IISc. The report, tabled in 1956, suggested that "the Institute should
The planning starts as early as January every
have an open week before the annual meeting
year when the date for the event is decided.
of the Court, during which the Institute may be
The Committee then requests the various
visited, both by members of the Court and the
departments to put together a list of activities
general public." The suggestion found support
that they would like to showcase and provide
from JRD Tata, then President of the Court
it with an estimate of the cost of each activity.
It also asks the departments to identify volunteers for manning the help desks to be set up around the campus. Based on this input, the Committee finalizes the activities and allocates the required funds.
Even as the activities are put together, the Committee focuses on advertising Open Day to the public, particularly in schools and colleges. It also works towards ensuring adequate security for the event.
Thousands of school children thronged IISc
"It is always challenging to organize a big event
Open Day is organized to showcase research
like the Open Day," says Krishnamurthy. "But we
in the Institute and communicate important
now follow a set protocol which makes it easier.
concepts in science and engineering to the
We also have efficient staff who help prepare
for it," he adds.
Based on the suggession, the first Annual Week was organized in March 1957. In the years that followed, Open Days were spread over two or three days. However, this practice was discontinued and an Open Day was organized intermittently. More recently, it has become a regular feature in the Institute's calendar. The day-long science carnival is held on (or close
to) 3 March, the birth anniversary of JN Tata,
the founder of the Institute.
One of the many help desks that were set up around the campus
Connect Volume 3 • Issue 2
"It is always challenging to organise a big
event like the Open Day"
Activities
As in previous years, this year's Open Day
too sought to mix fun and science in equal
measure. Some took the hands-on approach
to a new level: visitors themselves became
subjects in experiments. For instance, this
approach was used in the ‘Incredible Shrink
Machine', an experiment designed by students
from the Centre for Neuroscience, one which
used an optical illusion (see photograph on
Page 4) to explain how the brain perceives the
size of an object.
Aeroshow, one of the more popular events
experiences that people could relate to. Vignesh AN, a Master's student who helped design a few of these puzzles, claims that some of the solutions surprised even mathematicians. "It is amazing to see some people design unconventional techniques to solve a puzzle," he tells CONNECT. The prizes for the winners included books related to mathematics and famous mathematicians.
Though there are new activities every year, some like the Aeroshow, organized by the
Department of Aerospace Engineering, have
proven to be so popular that they have become
Solving a puzzle
regular features on Open Day. Aero enthusiasts
Other departments, such as Mathematics,
from different flying clubs were also invited
came up with their own ways to engage
to showcase their models. Among them was
visitors. Besides a treasure hunt, it also had a
Sandeep, a school student, who made his
collection of puzzles. These puzzles, of varying
own plane from scratch. "It feels awesome to
levels of complexity, were based on real-life
demonstrate my model here," Sandeep says.
Connect Volume 3 • Issue 2
would like to make this a regular feature here at IISc. It is a great place to find people with lot of energy and talent."
The driving force behind Open Day's diverse activities is the student community. It is the students who decide on the learning goals, plan and design the exhibits, and communicate the underlying science to visitors. S Amitash, a PhD student from the Department of Biochemistry, explained to CONNECT why he enjoyed the experience. "It helps me evolve as a researcher. The main essence of science is to communicate what we are doing in the lab. Otherwise there's no use [of doing science]", he asserts. He and
his lab-mates showcased a model that depicts
DNA replication; he also explained to visitors
the repair mechanisms found in animal cells
Painting workshop
But Open Day at IISc is not all about science.
to fix errors that sometimes arise during the
One such pleasant diversion from science
replication process.
was a stall set up by a non-governmental organization SEVITA, on invitation from the
"It helps me evolve as a researcher"
Centre for Product Design and Manufacturing.
For their part, visitors have the opportunity to
SEVITA organized a painting workshop to
see science in action, learn scientific concepts,
make visitors aware of India's traditional art
and appreciate the diversity of research pursued
forms, many of which are dying. Elated on
in IISc. The experience also motivates many
being invited to conduct the workshop, Devaki
youngsters to consider a career in science and
Rao, the founder trustee of the NGO says, "We
engineering. And for some, it provides greater clarity on what they want to do with their lives. For instance, Martin Jose, a class IX student from St Joseph's Boys High School, was certain that he would become a doctor before he came to Open Day, but not what he would specialize in. He now aspires to become a neurologist after watching a live demonstration of brain
activity using EEG (Electroencephalogram) at
the Centre for Neuroscience.
Demonstrating DNA replication and repair
Connect Volume 3 • Issue 2
Another consequence of the large crowds on
Ironically, the success of Open Day has led to
Open Day is significant increase in the number
some new logistical challenges in recent years.
of motorized vehicles in the campus. This year
One such issue the Institute has been grappling
even saw the odd traffic jam, an unprecedented
with is the management and disposal of
sight in IISc. Though a shuttle bus service was
waste produced due to the large number of
arranged to ferry visitors, it was not sufficient,
people who visit the campus on this day. The
according to Jayaram. He, however, believes
responsibility of dealing with this problem
that the traffic situation will improve next year
was shouldered by members of IISc Family
when the Committee plans to set up parking
and Friends and Solid Waste Management
lots at the various entrances and arrange more
Initiative of IISc (SWaMII) this year. Colour
frequent shuttles within campus.
coded bins were placed all over the campus to facilitate waste segregation. Volunteers at the
With an increase in the number of departments
help desks guided visitors on proper disposal
and a consequential upsurge in the number of
of trash. Food vendors were encouraged to
activities on Open Day, visitors find it difficult
use recyclable materials. "We know Bangalore
to cover all of them on a single day. "I went
has a huge waste disposal problem and want
crazy in the Biological Sciences building. It had
to contribute our bit to mitigate it. We are very
so many exciting displays. But I was not able
happy to see that it has worked," says Kavitha
to go through all of them as there were very
Harish, a member of IFF. "A good job was done
long queues and I was afraid that I might miss
to segregate waste and we should keep up this
the Aeroshow!" exclaims Anant Caprihan, a
discipline at all times," adds Vikram Jayaram, the
class V student. Caprihan's views are shared by
Chair of the Open Day Committee and also the
many others, including Vinay Dubey, Anamika's
Chair of the Division of Mechanical Sciences.
father, who suggests that the Institute should consider throwing open its gates to visitors for
"We know Bangalore has a huge waste
an entire week instead.
disposal problem and want to contribute our
bit to mitigate it"
(The author acknowledges the help of the following: Sowmithri Ranganathan and Manu Rajan for sourcing and researching archival material, and Karthik Ramaswamy and Nithyanand Rao for reporting on some of the Open Day activities)
Increasing traffic has become a challenge
Connect Volume 3 • Issue 2
FULFILLING THE PROMISE
As they depart from the nest that has nurtured them for the last four years, CONNECT takes a closer look at
where students from the second batch of the BSc (Research) course are headed
SUBHAYAN SAHU
Come September, Suhas Mahesh, currently
had focused exclusively on postgraduate
a senior undergraduate (UG) student in
IISc, will be joining Oxford University for his PhD in condensed matter physics, with the
Focus on Research
prestigious Rhodes Scholarship under his belt.
Not surprizingly, a majority of the students
Only the third Rhodes Scholar in the Institute's
graduating this year intend to pursue a career
107-year-old history, Suhas, who will graduate
in research. "Like most of my batch mates, I
later this summer, is part of the second batch of
joined IISc with an interest in research [and]
IISc's four-year Bachelor of Science (Research)
the biggest benefit of being a UG student at
programme which started in 2011. Until
IISc is the postgraduate nature of the Institute,"
then, IISc, India's premier research institution,
says Suhas. Balaji Jagirdar, Professor, Inorganic
Connect Volume 3 • Issue 2
and Physical Chemistry, and one of the two
by itself [and] having both biological and
Associate Deans of the UG Programme, concurs
mathematical training is useful for doing this
with this view. "Students joining this Institute
experience all the research activities that go on here and the path for the students to go into a
Climbing the Research Ladder
career in research is well laid out," he adds.
De and Gumani along with many other fourth year students have already bagged offers from
The course work emphasizes hands-on
some of the best universities in the world,
research in world-class laboratories, ensuring
including Caltech, MIT, Harvard, Cornell, Yale,
that these young minds appreciate the rigors
Berkeley, Princeton, University College London,
and joys of doing science. Experiments in
Max Planck Institutes and Oxford. Though
laboratories compliment lectures taught by
going abroad to pursue graduate studies is a
faculty members who are among the best
popular option, a few students are considering
researchers in their respective fields. At the end
doing their PhDs in India. In the past, most
of their first year, students major in any one of
Indian universities required a Master's degree
the following subjects: Biology, Chemistry,
for admission into a PhD programme. "However
Environmental Science, Materials, Mathematics
that situation is changing," clarifies PS Anil
or Physics. In their final semester, students also
Kumar, also an Associate Dean and Associate
do a research project with one of the several
Professor, Department of Physics. He adds that
faculty members of the Institute. This emphasis
opportunities for research for UG students,
on research cannot be overstated, feels Kishalay
both within and outside India, will increase in
De, a fourth year Physics major, who is going to
the near future. He says, "More universities are
Caltech for a PhD in astrophysics.
taking note of the UG programme in IISc, and hence the placement scenario is only going to
improve with time."
As part of their curriculum, students are also expected to take courses in engineering and
"More universities are taking note of the UG
the humanities. The engineering courses allow
programme in IISc, and hence the placement
them to explore the real-life applications of the
scenario is only going to improve with time"
basic sciences, while the humanities courses
Staying Home for Another Year
give them an opportunity to understand the social context in which science is done. The
But not all students who wish to pursue
interdisciplinary nature of the curriculum
research are leaving the Institute. At least not
has been recognized and appreciated by the
yet. After four years of study, IISc's UG students
students. Harsha Gumani, a graduating Biology
have the option of staying back for a fifth
major, who has received the sought-after
year to earn a Master's degree at the Institute
Wellcome Trust Fellowship for her graduate
itself, an option that a number of graduating
studies, says, "My chosen area of research is
students are planning to exercise. According to
neuroscience, a field which is interdisciplinary
Anil Kumar, this gives students an opportunity to investigate their final year research project
Connect Volume 3 • Issue 2
more deeply and also to explore other avenues
Many of the top rankers in these entrance
that may lie ahead of them. The precedent to
exams have also received offers for PhD and
continue at IISc for another year was set by the
Master's programmes in foreign schools.
batch of 2011, when 47 out of the 83 enrolled students opted to get a Master's degree at IISc.
Exploring Other Options
For instance, Pranav Mundada, decided, in his
Though the UG programme is designed to help
final semester, that he wanted to work in a
young students become researchers, it also
new field, and therefore stayed back. This year,
provides students with the skills required to go
he will be going to Princeton University for a
into the private sector. For instance, Abhinav
PhD to "try to make a fault tolerant quantum
Jain, who graduated last year, is a financial
analyst in Ernst and Young. He believes that though taking up a job immediately after
graduation is not yet a popular choice, there
At least three of them from this cohort of
are ample opportunities in the corporate world
graduating students are planning to study
for IISc's UG students. This year saw Fortune
economics in graduate school, a subject
500 companies like Goldman Sachs, Capital
that they did not major in. Sabareesh
One and Walmart coming to IISc, specifically
Ramachandran, a Mathematics major, is one
looking to recruit UG students. One such recruit
of them. He is headed to the London School of
is Sameer Shah, a fifth year student majoring in
Economics for a Master's in Economics, armed
Mathematics, who was hired by Walmart as a
with a Commonwealth Fellowship. "I intend
to work in public policy or developmental economics. I think the [Humanities] course
Environment of Excellence
on governance made me look at this career
As the programme gets older by a year, UG
option more seriously. I find in economics a
students at IISc, enriched by its environment
nice avenue to work on pertinent social issues
of excellence in research and pedagogy, have
while also using the analytical abilities that we
more than just lived up to the faith imposed on
developed in our maths courses," he says.
them by the Institute. Their stories of success are testament to the quality of education they
Acing Entrance Exams
have received. Suhas, who is also a connoisseur
Another indicator of the quality of the UG
of classical languages, ends with an old Sanskrit
programme is how well IISc's students have
been doing in the national-level entrance
santah sadābhigantavyā yadi nopadiśantyapi
exams for graduate programmes. This year,
yāstu svairakathāstesām upadeśā bhavanti tāh
Tapan Goel, a Physics major, has stood first in CSIR NET Physics; Ullas Chembazhi, majoring
"Keep the company of the wise, even if they aren't
in Biology, has got the first rank in GATE
teaching lessons.
Biotechnology and Nidhin Kurian, a Materials
For whatever they tell in passing, they turn out to
major, has topped the GATE Materials exam.
Connect Volume 3 • Issue 2
In conversation with guests of the Institute
MARESI NERAD: EQUIPPING YOUNG
RESEARCHERS WITH PROFESSIONAL SKILLS
MEGHA PRAKASH
skills, the role of mentorship and other issues concerning higher education.
Q Tell us about CIRGE and its activities.
The Centre, set up in 2002, focuses on doctoral education with three emphases: PhD career path studies, international research synthesis workshops, and evaluations (formative and summative) of theme-based, interdisciplinary, flagship doctoral programmes in the US and Europe.
So far, CIRGE has undertaken three National
PhD Career Path Studies. The studies surveyed
PhD recipients five to ten years after they
completed their doctorates. These surveys
Maresi Nerad is a professor of higher education
inquired about the retrospective assessment
and the founding Director of the Center for
of their doctoral studies, the career paths from
Innovation and Research in Graduate Education
the time they completed their degrees to the
(CIRGE) at the University of Washington in
time of survey completion, as well as on their
Seattle, USA. In January 2016, Nerad spent a
satisfaction with their current employment. In
month as a Visiting Professor at the DST Centre
order to understand better the reasons behind
for Policy Research in IISc. During her visit, she
career decisions of the surveyed men and
conducted a workshop for graduate students.
women PhDs, these surveys tracked not only
She also gave a lecture on ‘Issues in Doctoral
the career path, but also the ‘family path', that
Education and Innovation Policies: Looking
is the career of the spouse, the birth and age of
Beyond One's National Horizon' at the Centre for
children, and the need to take care of parents.
Contemporary Studies. After the workshop, she spoke to CONNECT about CIRGE's activities,
An interesting result that emerged from these
the need to equip researchers with professional
surveys was that a majority (two-thirds) of
Connect Volume 3 • Issue 2
women in the United States with a PhD had a
Quality of Doctoral Education (2014). And a
partner who also had a PhD, or a medical or law
third book on Intellectual Risk-taking in Doctoral
degree. But only about a quarter of the men
Education, is in progress. These workshops also
had a partner who had invested in education
help us understand the issues and challenges
as much as they had.
in doctoral education within different national higher education systems.
Further analyses of the survey data addressed questions such as the importance of acquiring
The third focus of CIRGE activities supports the
competencies in professional skills, teaching,
process of innovative doctoral programmes
time management, grant writing, working
while they unfold and provides ‘in time'
effectively in interdisciplinary teams, knowing
feedback to the faculty who run these special
how to manage budgets and people. In
short, it sought to understand professional competencies beyond the knowledge of the
Q You conducted a workshop for doctoral
subject and research methodologies. We
students here at IISc as well. Can you tell us
found that doctoral students who had done
more about these workshops? How do the
workshops that addressed these issues took
participants benefit from them?
a shorter time to graduate. Our studies also
The goals of these doctoral student workshops
inquired whether working as a postdoctoral
are to make the students aware that today an
fellow in a more reputed laboratory upped
independent researcher needs to have more
one's career prospects.
competencies than the traditional academic skills, to better comprehend the student-
"We found that doctoral students who had
advisor relationship and to learn to present
done workshops that addressed these issues
one's dissertation in a limited time (say in 5
took a shorter time to graduate"
minutes) to people outside one's field without
The international research synthesis workshops
using disciplinary jargon. I often employ "role-
address the interests of many countries around
playing" in these workshops to facilitate a
the world in doctoral education in light of
better understanding of the delicate advisor-
national innovation policies. In these week-long
advisee relationship. Globalization has only
workshops, funded by the National Science
accentuated the need for the development
Foundation (NSF) and co-sponsored by the
of more professional skills beyond the pure
host country of the workshop location, CIRGE
academic skills. Many countries—Australia,
brings together experts in doctoral education
New Zealand and those in Europe—have been
from different countries. We have published
organizing professional skills workshops for
two books on doctoral education that resulted
their doctoral students as a means of improving
from these conferences: Towards a Global PhD
career preparation.
(2007) and Globalization and its Impact on the
Connect Volume 3 • Issue 2
Q During the workshop you emphasized
for higher social recognition that resulted in
"professional feedback". Why is this
the conceptualization of such a degree. They
are different from a research doctorate in that there is no original research involved. Rather
We learn more when we receive feedback on
than generating original research, the focus is
our work from colleagues in a professional way.
on applying and using knowledge in different
By this I can learn what was good and what
contexts. I think both these types of doctorates
we can improve upon, and receive concrete
are desirable and have their place in society.
suggestions on how to do this. In conferences that I have attended, I have noticed students
Q How important is it to have a mentor in
become startled or baffled when posed with
queries after presentation of their papers, and they struggle to answer them. This may well be
Though we do learn from experience and
because the question is not well understood or
often by ourselves, I believe a mentor can be
the feedback is discouraging. Students need to
extremely beneficial. A mentor need not be just
learn to stay calm, listen, and ask if they do not
the dissertation advisor; he or she can be from
understand the comments. They also need to
another area or discipline or even from another
learn how to become a supportive colleague
institution. A mentor taking the mentee under
by providing feedback that is constructive
his or her wing, so to speak, helps the protégé
with concrete suggestions and do so also by
to set goals and standards, protects the protégé
pointing out the positive aspects. This makes
from others in a way that allows room for risk
the presenters more comfortable. The same
and failure, and facilitates successful entrance
applies to any work environment where
into academic and professional circles.
collaboration and discussion is involved. One of the objectives of my workshops is to train
"Though we do learn from experience and
students to appreciate the contribution of co-
often by ourselves, I believe a mentor can be
workers with positive feedback and also point
out ways and means of improvement.
Q Did you have a mentor?
Q What are your views on the two different
Yes. While in Germany, a professor in sociology
kinds of doctoral degrees—industrial and
was my mentor. I continued consulting with
research—awarded in some universities
her, even while pursuing my doctoral studies in
the US. And at the University of California (UC)
What does an industrial doctorate mean in
Berkeley, the Dean of the Graduate Division, also
India? If this means professional doctorates,
a nuclear chemist, sponsored me professionally,
such as a doctorate in nursing, social work,
made me aware of mistakes before they saw
audiology, or physical therapy, then I am
the light of the day, taught me how natural
familiar with this degree. In the US, professional
and social scientists complemented each
associations of these fields have been pushed
other and how to successfully design policies
Connect Volume 3 • Issue 2
for graduate and postgraduate education
countries. In the US, the faculty-student
in a given environment. I felt protected and
relationship tends to be less formal than in
guided in the early days of my career, and thus
Europe or Asia. In Japan and China, for example,
I would call him a mentor who also happened
the advisor is more a parent and is treated with
great respect. Given the increasing mobility of researchers, we would be wise to include
Q When and how did you get interested in
intercultural awareness in training the next
generation of researchers.
When I was 17, I spent the senior year in an
Q What else can be done to improve the
American high school under the American
quality of higher education?
Field Surveys programme. This exposed me to different cultures and kindled in me an interest in
Training in research has to begin early—right
international education. In Germany, I opted to
at the undergraduate level. Undergraduate
study political science and physical education.
students could be introduced to small research
After college, I spent two years as a high school
projects. There is a pressing need to develop
teacher. I became interested in organizational
critical thinking skills. There is also a need to
change and university education after realizing
train students in the art of asking the right
that my university education contributed little
kind of questions, and not blindly accept
to prepare me in my role as high school teacher.
whatever is stated by the instructor. This is
I wanted to change this. I decided to undertake
how independent thinking can be developed.
doctoral study in the field of higher education
The "flipped classroom" concept that turns the
to understand how change in organizations
traditional classroom on its head is already
comes about. I then moved to UC Berkeley
gaining ground in many universities. In this
to pursue my interest in higher education
model, instructional content is delivered in a
because Germany then did not offer a degree
video online. Students listen to the lectures
in the field of higher education.
online before they come to the class. In the classroom, the instructor uses the time to
"I became interested in organizational change
involve students in active discussions and
and university education after realizing that
hands-on exercises.
my university education contributed little to
prepare me in my role as high school teacher"
Q Does culture impact education?
Of course culture impacts education. Every student studying for some time in a different country will notice cultural differences and even talk about culture shock that extends to
educational settings. In doctoral education,
we find different advising cultures in different
Workshop participants
Connect Volume 3 • Issue 2
MARK TULLY: BBC'S VOICE OF INDIA
NITHYANAND RAO AND KARTHIK RAMASWAMY
only by his passion for the Indian Railways. These were among the many subjects he discussed in an interview with CONNECT. Here are excerpts from the conversation:
Q How independent do you think the Indian
media is?
I think the Indian media is independent of
the government. As with any media in a
democracy, there may be some newspapers
Born in 1935, Mark Tully, who spent the first 10
or TV channels which are pro-government and
years of his life in India, was sent to England to
some which are anti-government. But usually
further his education. After his schooling, he
their identity is fairly well-known. In fact, I
read History and Theology at Cambridge and
think in the fifty-odd years since I've known
considered becoming a priest in the Church of
this country, the media has actually become
England. He abandoned this idea in favour of
more independent and less dependent on
pursuing a career in journalism. He joined the
government information sources. Of course,
BBC in 1964 and moved to Delhi as its India
the major exception was the Emergency—I
Correspondent the following year.
don't think the media covered itself in great glory during the Emergency.
Tully was associated with the BBC for over three decades, both as a reporter as well as its Bureau
But I would like to point out the government
Chief in Delhi. For his contributions, he was
policy towards radio, where people are still not
made an Officer of the British Empire in 1985 and
allowed to broadcast independent news and
knighted in 2002. The Indian Government (which
current affairs. This is a grave infraction because
had barred him from entering India during the
radio is a very important medium, particularly
Emergency) awarded him the Padma Shri in 1992
in a country like India where large numbers of
and the Padma Bhushan in 2005.
people still don't have televisions.
Tully was in IISc in January to give a talk
Q You've worked mainly in radio. What's
organized by the Undergraduate Programme
unique about radio journalism?
and the Centre for Contemporary Studies. When CONNECT caught up with him at the Institute's
Radio broadcasting differs from print
Guest House, he had been deprived of a good
journalism for many reasons. One very obvious
night's sleep, thanks to a flight delay. He greeted
reason is that you have to be precise and quite
us cheerfully, but made sure that he conveyed his
simple. With TV, you have pictures to help; so
dislike for airlines and airports, a dislike matched
writing isn't as absolutely crucial.
Connect Volume 3 • Issue 2
I like radio because it makes me exercise my
Well, what you said is not absolutely true—you
writing skills. I like it because I love listening
have papers like The Guardian in the UK and
to radio. I think one of the greatest pleasures
The Tribune in India, which are run by trusts.
you can have in life is, for instance, listening to
Secondly, you have, in many democracies,
a drama on radio. It's similar to perhaps how
organizations like the BBC which are not run
your mother used to read to you when you
by the government.
The BBC, though a public broadcaster,
I think that radio has three great advantages
has always maintained, and fought for, its
which make it continually popular. You can
independence from the [British] government.
listen to it while you're doing other things.
In my experience of working at the BBC, I
That's why breakfast radio is so popular in
remember many occasions when the BBC came
Britain. It's a medium that leaves room for your
under pressure from the [British] government
imagination and therefore it's highly personal.
and resisted that pressure. I remember covering
And the third factor is its intimacy. I was once
the anti-[Zulfikar Ali] Bhutto movement; I was
speaking in a cathedral in Britain, and quite a
called in by the British High Commissioner in
lot of people came. I said that I don't know why
Pakistan and told that Mr. Bhutto did not like
so many people had come because I'm just a
me and it would be a good idea if I left the
journalist. At the end of it, an elderly lady came
country. So I said to him, "Well, that means I've
up to me and said, "You asked why I had come.
got to stay here for two more weeks," when in
I came because I think of you as my friend." This
fact I was hoping to go back to India.
is a unique quality of radio—that of intimacy. With good radio, you as a broadcaster should
But this independence depends very much on
be able to give many people the impression
the proprietor. If you have a proprietor like Mr.
that you're talking directly to them.
[Rupert] Murdoch, then your policy is dictated for you and you cannot escape from that. Then
That's why I think it's a very important, and a
you have to do your journalism within those
very popular, medium.
limitations. But it is important to realize that the public knows about that. Nobody in Britain has
"This is a unique quality of radio—that
of intimacy. With good radio, you as a
any doubts about where the political support
broadcaster should be able to give many
for The Sun or The Times lies. I think that is a
people the impression that you're talking
very important thing to remember about this
directly to them"
question that you posed.
Q Every media organization needs
Q Do you think a public broadcaster like
financial backing, either from the the BBC is still relevant and required? In the
government, politicians, business houses
Indian context, do you think Doordarshan
or philanthropists. How does it survive
and the All India Radio do a reasonable job?
the scourge of the agendas of the financial
stakeholders, whoever they may be?
I think government broadcasters like AIR and Doordarshan have limited impact because
Connect Volume 3 • Issue 2
everyone knows that they are the voice of the
Q As an editor, how do you decide what's
sarkar. One of the reasons why the BBC was
newsworthy? How do you balance the need
very influential in the 1960s, 70s and 80s was
for reporting good news along with the
because the only other available broadcasters
"man bites dog" stories?
from within India, both on radio and TV, were the government ones and everyone
Well, this is an old question. At the BBC, I once
knew that they carried government news.
worked on a programme called the Good News
Therefore, people turned to the BBC. So I think
programme. We used to scour the world's
that governments which rely on government
papers for good news, and we got quite a lot
media too much are making a mistake and are
of good news, but we didn't get very many
underestimating their audience.
listeners. So this is a problem. You're absolutely right that sensationalism is something which is
"I think that governments which rely on
sometimes quite difficult to avoid. But I think
government media too much are making
there's a way of balancing this to some extent
a mistake and are underestimating their
by having thoughtful and in-depth articles
rather than just news stories. In all journalism,
Q Do you recall any specific cases where
balance is a very difficult thing to achieve.
you were put under pressure by the
"At the BBC, I once worked on a programme
Indian government, other than during the
called the Good News programme. We used
to scour the world's papers for good news,
and we got quite a lot of good news, but we
During the Emergency, we were thrown out of
didn't get very many listeners"
the country. And we've been attacked often in the [Indian] Parliament.
Q You've been awarded the Padma Bhushan,
you've been knighted, won several other
There were complaints made quite often
awards. What do these awards mean to you?
about specific TV films which were made. One example was a film about the cleaning of the
Of course, it's a great honour. But I don't call
Ganges when Rajiv Gandhi was the Prime
myself Sir Mark Tully, although some people
call me that. I certainly would not put Padma Bhushan on my card or anything like that. I
I always say about journalism: you can question
wouldn't like to boast about them. At the same
the balance of the piece, and as a journalist you
time, I don't want to diminish the importance of
have to admit that you sometimes get things
these awards, because other people have given
wrong. If you don't admit that, you're either a
them to me and it would be very ungenerous
liar or an idiot—an idiot if you don't recognize
to say that it doesn't matter. But I'd also like to
it. But I can recall no real incident where we
say that I hope they have not made me less
were put under pressure. Mind you, by this
accessible to people or turned my head.
evening, I might have remembered. [Laughs]
Connect Volume 3 • Issue 2
DT MOURYA: DIRECTOR, NATIONAL
INSTITUTE OF VIROLOGY
MANBEENA CHAWLA
country's priorities. There are many emerging and re-emerging viral diseases spreading in our country. A large number of people are getting affected with morbidity and mortality, thereby affecting public health. Keeping these things in view, the agenda and priorities are decided by the Institute.
Q Do you miss active research?
In addition to all the administrative
responsibilities, I am actively involved in
Established in 1952, the National Institute of
scientific activities and I also have my own
Virology (NIV) in Pune is one of the major institutes
research projects. It is really tough to take time
of the Indian Council of Medical Research (ICMR).
out for science, but somehow I try to manage
It houses a BSL-4 (Biosafety Level 4) facility which
to do it by working long hours. But the time I
allows researchers to work with pathogens that
want to give to science has reduced because
could cause severe to fatal diseases in humans,
of so much administrative work, travel and
and for which vaccines or other treatments are
not available.
Q What measures are we taking to tackle
NIV is headed by DT Mourya who took over as
the Zika virus, especially since there is now
its Director in September 2011. In his illustrious
increased trade and travel between India
career, he has received several honours, including
and South America?
the first Dr. T Ramachandra Rao ICMR Award in 1990 for his work in the field of medical
Firstly, we are making efforts for preparedness
entomology.
for Zika. If it comes to India, we want to make sure that we will be able to contain the disease.
Mourya was in IISc on 11 April, 2016 to conduct a workshop titled Biorisk Preparedness in
We will also have to consider our research
Laboratory Setting, during which he gave
priorities. For instance, the Zika virus is a
several lectures. He took a few minutes off from
flavivirus similar to the dengue virus, but is
his packed schedule to talk to CONNECT.
unlike chikungunya, which is an alpha virus. So by taking such factors into consideration, it will
Q As the Director of NIV, how do you decide
help us understand aspects of its biology such
on your priorities and agenda?
as how it replicates. This will also help in the
As the Director, I decide on priorities based on
surveillance programme and in the detection
the mandate of the Institute, and also on the
of this virus in the vector.
Connect Volume 3 • Issue 2
Q In 2014, a study showed that the number
Yes, we have opened 3 field stations now : one
of dengue cases were vastly under-reported
is in Bangalore itself, one is in Kerala, and third
in India. Why?
is in Gorakhpur [in Uttar Pradesh]. The country
It is unfortunately very common in India,
is vast and we need to understand disease
not just for dengue, but for other diseases
scenarios from a regional perspective. A
as well. The problem is that good diagnostic
disease may be different in Himachal Pradesh
tools are still not available, such as a good
as compared to Karnataka. ICMR has taken
ELISA test [a test to determine the presence
initiative to establish Virus Research Diagnostic
of antibodies generated within the patient's
Laboratories [VRDLs] in all states to address the
body in response to any infectious disease],
issue of viral infections.
so that proper IgM [Immunoglobulin M, the
Q What will be your priorities in the coming
first and most common antibody to appear
in response to an antigen] monitoring can be done. Thereby, we can understand the number
There are two main priorities. The first is in the
of cases and the spread of the disease. Disease
area of respiratory infections as they spread
burden estimation is also necessary.
very fast. Many emerging infections like H1N1 spread through the respiratory mode.
Q What is the status of polio in India? Has it
Besides this, many people are not even aware
been completely eradicated?
of diseases being caused by RSV [Respiratory
Type 2 polio virus has already been eradicated
Syncytial Virus]. We now know that about 10%
and now we are in what is called a "shift
of people suffering from influenza are infected
period". So in this shift period of 6 months, we
because of RSV. The second priority is viral
have stopped administering children oral polio
hemorrhagic fever. We also want to focus on
vaccinations. When this vaccination is given,
immune therapeutics because there are many
it produces immunity in children, but also
viral diseases for which anti-virals and vaccines
replicates in the body. And so it is released in
are not available.
the environment through excreta which has
Q You are here to conduct a workshop on safe
to be reduced. Vaccine-associated outbreaks
laboratory practices. Tell us more about it.
have been known for a long time; so nobody wants to take that risk. Now, Inactivated Polio
One thing that I have realised in my 15 year-
Vaccine [IPV] has been introduced, which will
career in biocontainment is that there are
help wipe out this virus. The combined effect
a lot of lacunae when it comes to following
of IPV and oral vaccine can provide additional
safety protocols in laboratories working on
protection to the children. Very soon, possibly
pathogens. We plan to create and enhance
by 2017, we should be able to complete this
knowledge, as well as increase awareness
task of eradication of the disease.
about this simple, yet important responsibility in all important institutes working on
Q NIV is active in setting up field units in
infectious agents. So we are conducting 1-5
different parts of the country for studying
days workshops on basic safety protocols in
viral diseases. How do you decide where
institutes across the country.
they should come up?
Connect Volume 3 • Issue 2
HOT OFF THE PRESS
Recent research highlights from IISc
Compiled by NITHYANAND RAO from press releases written by the SCIENCE MEDIA CENTER*
Light-activated iron compounds to fight cancer
Researchers from the Department of Inorganic and Physical Chemistry and the Department of Molecular Reproduction, Development and Genetics have
discovered that a class of inorganic iron compounds
called iron (III) catecholates can be used to kill cancerous
Cour These compounds are activated when irradiated with red light. On being administered to a cancer cell,
they attack its mitochondria—the organelle which produces energy—thus killing the cell. This method avoids the problems of skin sensitivity caused by organic drugs. It is also extremely selective because it is activated only by light.
The team now aims to investigate the action of this anti-cancer drug in animal models.
Published in: European Journal of Inorganic Chemistry
Read more at: http://dx.doi.org/10.1002/ejic.201501105
METEOROLOGY
An improved rainfall detection model
How termites fortify their mounds
Detection of rainfall over land using satellite images
Researchers from the Centre for Ecological Sciences
is tricky, since the microwave radiation from land
and the Department of Civil Engineering have
heated by the Sun obscures the radiation from rain
discovered how Odontotermes obesus, a fungus-
clouds. The variation in land cover poses another
growing termite, alters the physical and mechanical
properties of the soil in order to make the mounds strong and stable.
Now, researchers from the Department of Civil Engineering have developed a new model for
They compared the soil in termite mounds to the
detecting rainfall. The team tested their model
surrounding soil, and found that the soil particles in
on satellite data from the basin area of the river
the mound were smaller. Besides, through a process
Mahanadi and compared the results with actual
called "biocementation", the termites strengthened
rainfall data for select events from ground-based
the soil tenfold. It involves making little boluses of
sources. The model detected rainfall in 95% of the
soil using their own secretions. Biocementation also
case study events.
makes the mound less susceptible to erosion and collapse.
Published in: Hydrological Sciences Journal
Read more at: http://dx.doi.org/10.1080/02626667
Published in: Environmental Geotechnics
Read more at: http://dx.doi.org/10.1680/
jenge.15.00036
* Science Media Center is a joint initiative of IISc and Gubbi Labs
Connect Volume 3 • Issue 2
Stem cells for the heart and the brain
Studying stem cells has become a popular area of research in recent years because of its enormous potential in treating tissue damage.
Researchers from the Department of Chemical Engineering
and the Materials Research Centre took a step in fulfilling
this potential when they used a pulsed current to
A induce stem cells to transform into heart cells, and a direct current to transform them into nerve : GREESHM cells. In both cases, the current was transmitted using gold nanoparticles, which through tesy "electroactuation" exerted mechanical forces on the stem cells. This technique could be used to Cour differentiate stem cells for tissue engineering and regenerative medicine.
Published in: Biomaterials
Read more at: http://dx.doi.org/10.1016/j.biomaterials.2015.10.078
Garlic-artemisinin combination effective against
A new TB vaccine candidate
Researchers from the Department of Microbiology
Artemisinin, the discovery of which won the 2015
and Cell Biology, collaborating with those from
Nobel Prize in Physiology or Medicine, is widely
other institutions in India, have identified a new
used to treat Plasmodium falciparum, the most
candidate vaccine for tuberculosis.
lethal form of malaria. However, the parasite is increasingly becoming resistant to artemisinin,
The researchers recruited groups of healthy
especially in parts of Asia. The WHO, therefore,
volunteers who have a latent TB infection—the
recommends using artemisinin in combination
bacterium Mycobacterium tuberculosis being
with other drugs.
present in a dormant state—and those with active TB. They treated blood samples of both groups with
Researchers from the Department of Biochemistry and
various peptides which are smaller parts of Rv1860,
the University of Birmingham have found that a garlic
a protein secreted by the TB pathogen. This was
concentrate along with arteether, a semi-synthetic
found to stimulate CD8+ T cells, which are involved
derivative of artemisinin, is an effective combination
in the human body's immune response. This effect
to combat malaria caused by Plasmodium berghei,
of Rv1860 was significantly greater in the volunteers
a mouse analogue of Plasmodium falciparum. The
who had latent infection compared to those who
combination therapy worked successfully, while
had the active disease.
either drug on its own did not. What's more, the mice did not suffer a relapse.
The researchers next aim to validate the results with larger study groups.
The researchers are now studying the mechanism of garlic's anti-malarial action.
Published in: Clinical and Vaccine Immunology
Read more at: http://dx.doi.org/10.1128/
Published in: Biochemistry and Biophysics Reports
Read more at:
bbrep.2016.01.015
Connect Volume 3 • Issue 2
Storing hydrogen more efficiently
One of the major challenges in using hydrogen as a fuel is finding a way to store it efficiently. A material that has a carbon base with metal atoms "decorat-ed" on it does store hydrogen, but not as much as
AD and ABHISHEK KUM
it theoretically could. This is because oxygen atoms too get adsorbed by the metal atoms.
Now, researchers at the Materials Research Centre have come up with a way to enhance hydrogen
adsorption by "capping" the metal atoms with molecules called arenes. This alters the electronic structure of the metal atoms in such a way that the interaction with oxygen atoms is selectively blocked.
This solution could also be applied elsewhere, such as in gas sensing and catalytic systems.
Published in: International Journal of Hydrogen Energy
Read more at: http://dx.doi.org/10.1016/j.ijhydene.2016.02.081
COMPUTATIONAL CHEMISTRY
A tool to compute hydrogen bonds
Protein structure from sequence
A hydrogen bond is one in which a hydrogen atom
Researchers at the Molecular Biophysics Unit have
of one molecule is attracted to an electronegative
developed a method called "saturation suppressor
atom—such as a nitrogen or oxygen atom—of
mutagenesis" to predict which amino acids in a
another molecule. Hydrogen bonds are abundant
protein lie close to each other. This is important
in nature, playing an important role in determining
for predicting the structure and, therefore, the
the shapes and functions of biomolecules, including
function, of a protein from its specific sequence
DNA and proteins.
of amino acids. Traditional methods require high-quality protein crystals, which may not always be
A team at the Department of Computational and
Data Sciences has developed a Hydrogen Bonds Computing Server (HBCS, http:// bioserver1.
Suppressor mutations, which preserve protein
physics.iisc.ernet.in/hbcs/) which computes various
function, happen when mutations in one amino
properties of the hydrogen bonds in a given
acid are compensated for by mutations in amino
molecule, and also the estimated error in these
acids close by. A comprehensive procedure to
calculations. For this, HBCS uses a repository of
identify suppressors has now been devised. This
standard information about the 3D structures of
was achieved by creating an inactivating mutation
various biological macromolecules. Users can also
in a protein and then systematically searching for
input information about any other molecule whose
suppressors. Using mutations in several places, the
hydrogen bond properties they wish to compute.
researchers were able to piece together proximity information for multiple pairs of amino acids.
Published in: Journal of Applied Crystallography
Read more at:
Published in: eLife
Read more at: http://dx.doi.org/10.7554/
eLife.09532
Connect Volume 3 • Issue 2
DISPATCHES FROM THE LAB
In this section, we shine the spotlight on researchers from IISc who are making a splash
in their fields of research
BASED ON INPUTS FROM THE FEATURED RESEARCHERS
A CHOCKALINGAM (PROFESSOR, DEPARTMENT OF ELECTRICAL COMMUNICATION ENGINEERING) AND
B SUNDAR RAJAN (PROFESSOR, DEPARTMENT OF ELECTRICAL COMMUNICATION ENGINEERING)
RESEARCH IN LARGE-SCALE MIMO SYSTEMS
Multi-antenna wireless communication has
reliability. Large-scale multiple-input multiple-
become immensely popular because of its
output (MIMO) systems with tens to hundreds of
unique advantage of achieving increased data
antennas are being considered for 5G wireless
rate (without increasing bandwidth) and link
standards. Chockalingam and Sundar Rajan's
Connect Volume 3 • Issue 2
labs have made pioneering contributions in
More recently, recognizing the value and
the area of large-scale MIMO systems (now
importance of translating their research
popularly called Massive MIMO systems). They
output into practice, Chockalingam and
have developed near-optimal low-complexity
Sundar Rajan, jointly with DRDO and partners
receiver algorithms that broke the optimum
from industry, have developed a large-scale
receiver complexity barrier encountered in
MIMO system that uses 16 transmit antennas
large dimensions. These algorithms are rooted
and 20 receive antennas in the 2.5 GHz band
in artificial intelligence and machine learning,
Chockalingam and Sundar Rajan have also
algorithms based on local search and meta
authored a book titled Large MIMO Systems,
heuristics (tabu search, for example), belief
published by Cambridge University Press
propagation/message passing and Monte
in 2014. It is the
Carlo sampling methods. Ingenious ideas
first book to take
in these proposed algorithms with carefully
an in-depth look
balanced performance and complexity were
instrumental in the success of these algorithms
for signal detection in large-scale MIMO
tens to hundreds
systems. This collaborative research by these
two electronics communication engineers
Chinese edition of
resulted in the early development of the field
this book is being
of large-scale MIMO systems. They also have
several US patents granted in this area.
Their book on the subject
This collaborative research by these two
electronics communication engineers
resulted in the early development of the field
of large-scale MIMO systems. They also have
several US patents granted in this area
More recently, recognizing the value and importance of translating their research output into practice, Chockalingam and Sundar Rajan, jointly with DRDO and partners from industry,
have developed a large-scale MIMO system that uses 16 transmit antennas and 20 receive
antennas in the 2.5 GHz band. The basic design
and implementation approach for this system
are based on their patents on large-scale MIMO.
A 20-Antenna MIMO Cube
Connect Volume 3 • Issue 2
GAUTAM DESIRAJU (PROFESSOR, SOLID STATE AND STRUCTURAL CHEMISTRY UNIT)
PIONEER IN CRYSTAL ENGINEERING
Gautam Radhakrishna Desiraju—one of India's
currently a member of the editorial advisory
most eminent chemists—joined IISc in 2009
boards of Angewandte Chemie, Journal of
after 30 years at the University of Hyderabad. It
the American Chemical Society and Chemical
was he who, in his 1989 book, coined the term
Communications.
"crystal engineering", which he defined as "the understanding of intermolecular interactions
In their research, Desiraju's group uses
in the context of crystal packing and using it
a technique called nanoindentation, in
to design new solids with desired physical
collaboration with U Ramamurty of the
and chemical properties". He is also associated
Department of Materials Engineering, to
with terms such as "weak hydrogen bond" and
understand the mechanical behaviour of
"supramolecular synthon", now an integral
organic crystals and to correlate it with the
part of a crystallographer's lexicon, and is
properties of the molecules in these crystals.
one of the most highly cited Indian scientists.
With this tool, they have studied the properties
He was president of the International Union
of the active pharmaceutical ingredient (API)
of Crystallography from 2011 to 2014 and is
felodipine and also engineered the hardness
Connect Volume 3 • Issue 2
of an important API, omeprazole. Recently,
of a supramolecular combinatorial library can
they have also identified the structural
be profitably extended to the crystallization
features that enable organic crystals such as
process, with supramolecular synthons being
N-benzylideneaniline to be highly flexible.
the constituents of such a library.
Using nanoindentation, Desiraju's group
Desiraju's lab has also successfully improved
has studied the properties of the active
the physical and chemical properties of the
pharmaceutical ingredient (API) felodipine
diuretic drug hydrochlorothiazide using
and also engineered the hardness of an
various other compounds with which it can
important API, omeprazole.
Desiraju's research team has established for the first time dual mechanical properties in an organic crystal, namely pressure-
induced elastic mechanical bending and
temperature-induced crystal splitting. A
combinatorial crystal synthesis approach
has been explored to design ternary—three
component—molecular solids that constitute
the crystal structure landscape. This concept
Front and back cover pages of Desiraju's textbook co-authored by
Jagadese Vittal and Arunachalam Ramanan
Desiraju with his team
Connect Volume 3 • Issue 2
MATHEMATICS: BRIDGING
A closer look at contributions of researchers who seek to connect various scientific disciplines through
a common language
NITHYANAND RAO
Founded in 1956 as the Department of Applied
equal to that of any other maths department
Mathematics by PL Bhatnagar, an eminent
in the country," he says.
mathematician, the initial mandate of the Department was to provide mathematical
The name change reflected an expansion
training to students in the science and
in the research interests of the Department,
engineering programmes of the Institute.
which was earlier focused on areas considered
It took its current name in 1989 during CNR
as applied mathematics, such as the kinetic
Rao's tenure as the Director of IISc, a period
theory of gases and fluid mechanics, areas that
that Gadadhar Misra, the current head of the
Bhatnagar was active in. But this is not the case
Department, believes led to a reinvigoration.
today. "Unlike many other institutes, we live
"He tried to put the Department on a footing
happily without having any biases about what
Connect Volume 3 • Issue 2
sort of mathematics should be done," adds
"When you see abstraction, you may not see
any applications directly. But abstraction
really makes mathematics more applicable"
Research
The research interests of faculty members in
Analysis, another major branch, is the study of
the Department are diverse. Traditionally, the
mathematical functions and how they change.
different areas of research in mathematics fall
The beginnings of analysis may also be found
within its "three pillars": algebra, analysis, and
in high-school mathematics curriculum in
geometry. These are, however, more than just
the form of calculus. Central to analysis is the
branches—they are also ways of thinking
concept of the limit of an infinite sequence
that permeate across the myriad avenues of
or of the sum of an infinite series—a quantity
research that mathematicians pursue.
that will not be exceeded, yet one that can never be reached no matter how many terms
Broadly speaking, algebra is the study
one considers. An example is the sequence
of operations that one can carry out on
of numbers 0.9, 0.99, 0.999, and so on, which
mathematical objects. The algebra that
approaches, but never reaches, unity. The
one learns in high-school might appear,
techniques of analysis applied to the abstract
superficially, to be the manipulation of
algebraic structures yield various avenues
symbols with the aim of solving various kinds
of research, pursued by Gadadhar Misra and
of equations. But trying to solve equations has,
over the centuries, often been fertile ground for creating new mathematics. Structures, or sets
A major topic in analysis is the study of
of elements which have common properties
partial differential equations (PDEs), which
and upon which one can define certain
are used to model many natural phenomena.
operations, that emerged from trying to solve
Nandakumaran studies PDEs, especially those
equations later became objects of study. The
that arise in applications such as medical
study of such structures, and operations on
imaging. Often, solutions for these equations
them, is what is today called algebra. Faculty
cannot be found in the form of exact formulae,
members of the Department who do research
which is where numerical analysis comes in,
in algebra are Dilip Patil and Pooja Singla.
the idea being to develop algorithms that can give approximate but reliable answers. Such
Such abstraction—developing a theory rather
techniques, some of which are employed
than techniques to solve individual problems—
by Thirupathi Gudi, do not merely generate
is what gives mathematics its power. "When
numbers, but provide insight into the
you see abstraction, you may not see any
phenomenon being studied.
applications directly. But abstraction really makes mathematics more applicable," says AK
The study of real numbers themselves, often
Nandakumaran, a professor in the Department.
integers, is called number theory. This line of
Connect Volume 3 • Issue 2
research is pursued by Soumya Das. Historically,
Topology, by contrast, is the study, especially
it was in trying to solve equations which had
in higher dimensions, of distinct shapes that
no solutions in the real numbers that the
can be twisted and stretched but not torn or
"imaginary" number—the "square root" of
punctured. Therefore, apples are topologically
- 1—was invented. This gave rise to complex
the same as oranges because it is possible to
numbers. The study of functions of one or
deform one (in your imagination, at least) into
more complex variables is, generally, what's
the other. They are, however, distinct from,
called complex analysis, which is the research
say, the rubber tube in a vehicle's tyre. The
area of Gautam Bharali and Kaushal Verma.
topologists in the Department include Basudeb Datta, Siddhartha Gadgil and Subhojoy Gupta.
The study of how a function can be expressed in terms of a set of more basic periodic functions
The Department also has a strong group,
is the subject of harmonic analysis. Faculty who
comprising Arvind Ayyer, Mrinal Ghosh,
study harmonic analysis include S Thangavelu
Srikanth Iyer, and Manjunath Krishnapur, that
and EK Narayanan. As such, it finds application
works on probability theory and stochastic
in any area of science and engineering where
processes. Ayyer studies, among other things,
signals need to be analysed.
Markov chains, which are models for systems that evolve randomly whose next state depends
Geometry, the third pillar of mathematics, is
only on the current state; Ghosh investigates
the study of shapes. Central to geometry are
stochastic processes that have applications in
higher-dimensional generalizations of shapes
financial markets and in other real-life systems;
called manifolds—the surface of a sphere or of
Iyer works on stochastic phenomena arising in
an inflated bicycle tube are familiar examples.
wireless networks, financial instruments and
Modern geometry involves studying these
their pricing, and interacting particle systems;
shapes from different perspectives. One of
and Krishnapur studies the theory of matrices
them, algebraic geometry, is the study of
whose elements are random variables.
manifolds that can be described using algebraic equations and studied using algebraic
G Rangarajan works on the applications of
techniques. It is pursued in the Department by
nonlinear dynamics in, for example, networks,
Abhishek Banerjee.
time series of various phenomena, and biological processes.
Another faculty member, Harish Seshadri, meanwhile, does differential geometry, which
employs the methods of analysis in the study of
The Department has 21 faculty members,
geometric objects. An example of a problem in
which, Misra says, is smaller compared to
differential geometry would be to understand
other major mathematics centres in India and
how heat flows from one part of a manifold to
abroad. Yet, the Department has more than 50
another, especially when there are multiple
students enrolled in the PhD and Integrated
paths available.
PhD programmes, with up to 15 new students enrolling every year.
Connect Volume 3 • Issue 2
Apart from the regular PhD and Integrated
people interested in mathematics, who do
PhD programmes, the Department also hosts
mathematics, who apply mathematics.
the PhD programme in Interdisciplinary
otherwise everybody works in isolation."
Mathematical Sciences. "The fact that we have
an Interdisciplinary PhD programme, housed
In 2012, DST expanded the
particularly in our Department, is a matter of
scope of the programme, and
great pride," says Misra. As he puts it, it's ideal
it was renamed as the National
for a student, who, for instance, "has solved a lot
Mathematics Initiative (NMI).
of differential equations but wants to really see
While still coordinated by IISc, events are
how the wings of a plane warp and influence
now held outside IISc too. "IISc continues to
motion in practice." This unique programme
be the nodal agency but the programme
gives students the option of doing their PhD in
now has a wider focus; it has spread out," says
an area of science that involves mathematical
Misra. Rangarajan, under whose leadership
work. Students can choose from various
IMI began, continues to be the Convener
interdisciplinary projects that are listed at the
of NMI. Every year, a committee headed by
time of admission. They could, for example,
Rangarajan, the Chairperson of the Division
choose supervisors from among those who are
of Interdisciplinary Research, decides a
part of the DST Centre for Mathematical Biology,
"theme"—an interdisciplinary subject area to
also hosted by the Mathematics Department,
focus on. The current theme is game theory
which brings together researchers from across
and optimization.
IISc to work on problems in biology, amenable to mathematization.
At IISc, NMI involves more than 35 faculty members
"The fact that we have an Interdisciplinary
Researchers from leading institutions all over
PhD programme, housed particularly in our
India, and abroad, also participate in this
department, is a matter of great pride"
Initiative, along with resource persons from national laboratories and the industry—
The Interdisciplinary PhD programme is a
something unique in India. "Though individual
part of the IISc Mathematics Initiative (IMI).
interactions were there, NMI provided
This initiative began in 2003 to encourage
a structure to these interactions," says
collaborative work between mathematicians
and other researchers across departments in the Institute who used mathematics in their
All these activities are housed in an inviting
research areas. Although the programmes—
two-storey building, its airy architecture
workshops, conferences, short courses—
reminding one of the all-encompassing nature
focusing on various interdisciplinary topics
of mathematics, and the welcoming façade
were held at IISc, people from outside were
putting its visitors—even those for whom
encouraged to participate, says Nandakumaran,
mathematics may have been a forbidding
who was involved with IMI from the beginning.
subject in school—at ease.
The aim, he says, was "to bring together all
Connect Volume 3 • Issue 2
Meet new faculty members who have joined IISc
SRIRAM GANAPATHY (Assistant Professor, Department
of Electrical Engineering) is from Thiruvananthapuram.
He completed his PhD from Johns Hopkins University,
USA, in modelling for audio and speech signals. After a
stint as a Research Scientist at IBM TJ Watson Research
Center, USA, where he worked on algorithms for dealing
with highly noisy speech signals, he is now in IISc. Here he
plans to pursue his research interests in signal processing,
speech processing, machine learning and deep learning
to extract information from speech and audio signals.
SARASIJ DAS (Assistant Professor, Department of Electrical
Engineering) received his PhD from the University of
Western Ontario, Canada. He pursued his postdoctoral
work at the University of Ontario Institute of Technology,
also in Canada. His research interests include smart
grids, power system protection and monitoring, grid
integration of renewable energy and power system data
mining and analysis.
JYOTHSNA RANI KOMARAGIRI (Assistant Professor, Centre
for High Energy Physics), originally from Hyderabad, did
her PhD from the Tata Institute of Fundamental Research,
Mumbai. Her research, done in collaboration with
Fermilab, USA, was in the area of high energy physics.
Komaragiri then did her postdoctoral studies at Simon
Fraser University, Canada. At IISc, she is part of the newly
formed Experimental High Energy Physics group.
Connect Volume 3 • Issue 2
ANAND SRIVASTAVA (Assistant Professor, Molecular
Biophysics Unit) was born and raised in Patna, Bihar. He
has an engineering degree from IIT-Kharagpur and a PhD
from Ohio State University for his dissertation on glass
transition temperature in thin films. He later joined the
University of Chicago, USA, as a postdoctoral researcher
to explore his interest in chemical-physics theory and
molecular modeling. Now at IISc, Srivastava's primary
interests are in the areas of mechanobiology and force-
induced conformation changes in proteins.
RAJIV SOUNDARARAJAN
Department of Electrical Communication Engineering) did his Bachelor's degree from BITS Pilani and went on to get his Master's and doctoral degrees in Electrical and Computer Engineering from the University of Texas at Austin, USA. His work in IISc is in the area of image and video quality assessment. He is interested in predicting the quality of visual signals that would be in accordance with how humans perceive them, and also in information theory.
VIBHOR SINGH (Assistant Professor, Department of
Physics) hails from Haridwar in Uttarakhand. He obtained
his PhD from the Tata Institute of Fundamental Research,
Mumbai, studying the condensed matter properties of
atomically thin system graphene. His postdoctoral work at
the Technical University of Delft, the Netherlands, was on
developing new opto-mechanical platforms based on two
dimensional materials and superconducting microwave
cavities. At IISc, he plans to set up an experimental lab
to probe the motion of nanoelectromechanical systems
in the quantum limit and their applications in quantum
information technology.
Compiled by MANU RAJAN and SUDHI OBEROI
Connect Volume 3 • Issue 2
BOOST FOR INFECTIOUS DISEASE RESEARCH
SUDHI OBEROI
Infosys Foundation has announced a financial
highlighted by G Padmanaban, a former Director
grant to the Centre for Infectious Disease Research
of IISc and currently an Emeritus Professor at the
(CIDR) at IISc to help broaden its research and
Department of Biochemistry, during a session of
also provide additional infrastructural support to
the Global Alumni Meet of IISc in June 2015.
Speaking to CONNECT, Dipankar Nandi, a
Infectious diseases like tuberculosis (TB), malaria,
professor at the Department of Biochemistry
HIV/AIDS, hepatitis and more recently SARS,
and Convenor of the committee that runs CIDR,
Ebola and Zika virus diseases are posing a threat
said that Sudha Murthy (Chairperson, Infosys
to human health around the world. With human-
Foundation, and an alumnus of IISc), who was
induced changes to the environment and
chairing this session, immediately offered to help
increased globalization, pathogens have become
CIDR in its plans for expansion.
more likely to switch hosts and spread across traditional geographic barriers, causing not
In an interview to CONNECT, Murthy stressed
just more frequent disease outbreaks, but also
upon the importance of advancing fundamental
epidemics. While some infectious diseases have
research in the area of infectious diseases and
been well researched and can be prevented, or
also developing new drugs and diagnostics.
cured, many others, particularly tropical diseases, have received far less attention. A major goal of
The support from Infosys Foundation, which will
CIDR, set up in 2013, is to help plug this gap and
be spread over five years, will help in building
address questions in infectious disease research
an annex to the Centre—this will house three
that are more relevant to countries like India.
laboratories and more office space. In addition, a small animal BSL-3 facility for research will
Currently, CIDR consists of a central lab, a state-
be built. The research team at CIDR will also be
of-the-art bio containment space known as the
expanded. It will recruit two Infosys Fellows who
Biosafety Level-3 (BSL-3) facility and office space
will conduct independent research. According to
for its researchers. In the past few months, the
Nandi, some of the money from the Foundation
will also be used to pursue another important
goal of the Centre: translational research.
to expand the scope of its
The Centre, which is already working with
researchers from all over the Institute to ensure an
interdisciplinary approach to studying infectious
diseases, also plans to organize seminars to
increase public awareness on the subject.
Connect Volume 3 • Issue 2
IISc AND GE INK AGREEMENT
RANJINI RAGHUNATH (WITH INPUT FROM Y NARAHARI)
In December last year, IISc and GE India Technology Centre signed an agreement to formalize their collaborative efforts in many different areas of research. The MoU was signed by Registrar of IISc, V Rajarajan, and D Umamaheshwar, Executive Chief Consulting
Engineer at GE Aviation, in the presence of
Anurag Kumar, Director of IISc.
Over the past decade, IISc has been working
believe in an open, collaborative approach to
on several collaborative research projects
innovation. With the convergence of the physical
with GE India Technology Centre, GE's largest
and digital worlds and the ability to connect
multidisciplinary R&D centre. To take this
like never before, the premium and benefit on
collaboration to the next level, Anurag Kumar
collaboration has never been greater. In India, we
and some of his senior faculty colleagues made a
have a strategic vision to build long term relations
visit to their facility in Bangalore, the John F Welch
with the premier institutes and IISc is one of
Technology Centre, in April 2015. At this meeting,
the top institutes we want to collaborate with,"
several broad areas such as energy, hybrid power,
said Umamaheshwar, speaking to CONNECT.
distributed control and optimization, big data
"We have chosen IISc because of its reputation,
analytics and Industrial Internet were identified
talent, and high-end research capabilities." IISc
for collaboration. In the following months,
and GE India Technology Centre have very similar
multiple workshops were organized in these
multidisciplinary research interests, he added.
focus areas involving IISc faculty members and GE researchers, paving the way for several joint
As part of the agreement, several high-impact
project ideas in these research areas.
projects in the identified areas will soon be launched under the aegis of IISc's Society for
"This MoU will go a long way in fostering high
Innovation and Development. Many of these
impact collaborations and push the frontiers
areas represent fields that GE is currently making
in exciting areas such as big data analytics,
strides and heavily investing in, apart from its core
distributed optimization algorithms for hybrid
engineering focus, according to Umamaheshwar.
energy systems, breakthrough new materials,
"The talent and research infrastructure at IISc
and the Industrial Internet," said Y Narahari,
will be a great value-addition to GE, while IISc
Chairman, Division of Electrical Sciences at
researchers will have an opportunity to leverage
IISc. "We are looking forward to harnessing
GE's expertise and industry insights," he said.
the synergy between academic creativity and industrial innovation."
At the MoU signing, IISc and GE also inked an agreement to implement Corporate Social
GE, which has a presence in 175 countries, already
Responsibility (CSR) projects at IISc over the next
has several such "umbrella" research agreements
with leading universities worldwide. "At GE, we
Connect Volume 3 • Issue 2
CAMPUS CHRONICLES
DESIGNING FOR A CLEANER NATION
about what they've already done in their own
silos—whereas here we're looking for creative
solutions which impact the lives of waste collectors. We wanted the participants to have
a much more interactive, engaging experience
than just another knowledge sharing session,"
said Gayitri Handanahal of Waste Impact.
Participants during the Reimagine Waste hackathon
Reimagine Waste, a "design hackathon", was
On the final day, the 12 finalists presented
organized at IISc by the Centre for Product
their solutions to a panel of judges comprising
Design and Manufacturing (CPDM), in
seasoned entrepreneurs, venture capitalists
association with the Centre for infrastructure,
and domain experts. The teams were quizzed
Sustainable Transport and Urban Planning
on various aspects of their proposed solutions,
(CiSTUP) and Waste Impact, an NGO. The event
such as the viability and marketability of
was spread across two weekends: 26-27 March
their ideas. The first prize was won by a team
and 2-3 April 2016. This hackathon was the first
from Infosys, Nitte Meenakshi Institute of
in a series of initiatives that aims to tackle the
Technology and Alliance University, which
growing garbage problem, particularly acute
built a system involving a smartphone app, a
in Bangalore.
wireless weighing scale, and a "gamification" platform that would enable waste collectors
Over 200 students from IISc and elsewhere
to record data about the waste collected at the
participated in this hackathon. Day one saw an
"Immersion" session in which the participants visited various facilities—dry waste collection
The finalists have also been given an
centres, incinerators, and landfills—across
opportunity to refine their ideas and come up
Bangalore and its outskirts. Based on this
with marketable ventures within 45 days. "We
first-hand knowledge, on day two, problem
would be happy even if one or two of these
statements were proposed and participants
ideas become viable enterprises which make a
were divided into teams, with each team
real difference on the ground. In addition, the
tackling one problem. Each team also included
hackathon serves to sensitize participants to
at least one waste collector as the domain
the problems of waste management in our city
expert. On day three, the teams were provided
and how they can be part of the solution rather
with the raw materials, tools and machining
than just the problem," Manish Arora, a faculty
facilities to "hack away" at the problem and
member from CPDM and one of the brains
come up with solutions within 24 hours. "In
behind this novel experiment, told CONNECT.
traditional workshops, participants only talk
NAVIN S
Connect Volume 3 • Issue 2
In the general panel discussion, moderated by NDTV journalist Maya Sharma, the panel raised critical questions, including those related to the perception of women scientists and the importance of their inclusion in decision making processes. One of the panelists,
From left to right: Anurag Kumar (Director, IISc), Kiran Mazumdar
Sandhya Visweswariah (Professor, Department
Shaw (Chairperson and Director, Biocon Limited) and Sandhya
Visweswariah (Professor, IISc) at WiSER 2016
of Molecular Reproduction, Development and
"If I can get institutes to realize that something
Genetics, IISc), felt that the criteria for recognition
special needs to be done to encourage both
in academia are tilted in favour of men.
young women students and faculty to prosper,
A second panel discussion addressed, among
then I would have achieved something," said
other issues, the dilemma that women often
Rohini Godbole (Professor, Centre for High
face in trying to balance family life and work.
Energy Physics, IISc), setting the tone for the
During the discussion, Narayan Sundaram
first Women in Science, Engineering and
(Assistant Professor, Department of Civil
Research (WiSER) conference. Organized by the
Engineering, IISc) admitted that men were
IISc Families and Friends and the IISc Alumni
aware of the problems faced by women in
Association on 2 April 2016 at the Institute,
various spheres of life, but often lacked the
the event brought together women, and men,
vocabulary to express their support. Usha
from industry and academia to discuss the
Vijayraghavan (Professor, Department of
obstacles that women researchers face.
Microbiology and Cell Biology, IISc) felt that the
In his introductory remarks, Anurag Kumar,
path is easier for the current generation than it
Director, IISc, highlighted the crux of the
was a few decades ago.
problem, referred to as the "leaky pipeline" phenomenon: The number of women pursuing
The final session featured roundtable
science drops dramatically as they climb career
discussions in which participants had
ladders (even though the percentage of girls
to propose, and later discuss with the
in schools and colleges is increasing). This
audience, practical solutions to address
was followed by a keynote address by Kiran
various issues such as gender harassment,
Mazumdar-Shaw, Chairperson and Managing
women's health, and security. In conclusion,
Director, Biocon Limited. Mazumdar-Shaw
Vijayalakshmi Ravindranath (Professor, Centre
shared experiences of the time when she
for Neuroscience, IISc) echoed a widespread
was building her company, which, she said,
sentiment when she said that she hoped to
made her more determined to create more
see a day when there are no "women scientists"
opportunities for women in leadership roles.
but just scientists who happened to be either women or men.
VRUSHAL PENDHARKAR
A version of this article appeared in IndiaBioscience.org
Connect Volume 3 • Issue 2
transmit and process information—and that on micro and nano electromechanical systems, and microfluidics.
The symposium had sessions on commercial products that resulted from research at
CeNSE—such as an air pollution monitoring
system named Envirobat, a glucometer being
commercialized by the start-up PathShodh,
Rudra Pratap, Chairperson of CeNSE, interacting with a participant
pressure sensors for Light Combat Aircraft
at Think Nano
The Centre for Nano Science and Engineering
and an advanced chemical vapour deposition
(CeNSE) organized a National Student
reactor for manufacturing graphene. There
Symposium, Think Nano, on 31 March and 1
was also a panel discussion involving CeNSE
April 2016. The event, being held for the first
industry partners, including Unilever, KAS
time, was co-sponsored by the Airbus group.
Technologies, Centum Electronics, and Analog Devices.
The idea behind conducting this event, said Rudra Pratap, Chairperson of CeNSE, was to
More than 180 undergraduate students from
spread awareness among undergraduate
all over the country presented their research
students about the research and career
ideas in the form of posters. They also got an
opportunities available in the field of
opportunity to visit various laboratories and
nanoscience. As part of the symposium,
the nano fabrication facility, and to interact with
faculty members at CeNSE hosted sessions
members of a panel of graduate students at
highlighting their research. This included work
CeNSE who shared their research experiences.
on developing photonics on a chip—using
DEBADRITA PARIA
photons rather than electrons to encode,
STUDYING CELLS AS THEY FLOW
Flow cytometry is a technique in which a stream of single cells or particles is passed through an illumination point, and hit with coherent
beams of laser light of specific wavelengths.
The information that the scattered photons
carry can be used to measure and analyze the
physical and chemical properties of the cells
or particles. This technology has found several
The "Build Your Own Flow Cytometer" session with William Telford
applications, particularly in medical research.
Connect Volume 3 • Issue 2
To help students learn techniques of flow
the National Institutes of Health, USA. The
cytometry, the 17th Indo–US Cytometry
"workshop also saw many other renowned
Workshop on Applications of Laser Flow
Cytometry in Biomedical Research was jointly
(University of Miami, USA), Zofia Maciorowski
organized by IISc, National Centre for Biological
(Curie Institute, France), Sumeet Gujral (Tata
Sciences (NCBS) and the International Society
Memorial Centre, Mumbai) and Vineeta Bal
for Advancement of Flow Cytometry, USA,
(National Institute of Immunology, New Delhi),
between 14–18 March 2016. Students who
deliver talks and conduct wet lab modules.
participated in the event, held at IISc and NCBS,
Some of the modules were also taught by
were selected from institutions across India.
scientists working in industry, leading to a healthy interaction between researchers in
The star attraction of the workshop was the
academia and industry.
"Build Your Own Flow Cytometer", a hands-on module conducted by William Telford of
TARU VERMA AND SYAMA SREEDHARAN
SOLID WASTE MANAGEMENT CONFERENCE
for instance, generate biogas from food waste instead of disposing it in bins. Composting in-house would also reduce the load on the Bruhat Bengaluru Mahanagara Palike (BBMP).
The conference emphasized the need to find scientific solutions for resource management and for waste disposal, especially in fast-
growing cities like Bangalore. It also underlined
Almitra Patel and Tejaswini Ananth Kumar at MSWM 2016
the importance of inclusive solutions that address the livelihoods of the waste-pickers.
A conference on Municipal Solid Waste
Both the BBMP and various NGOs have been
Management (MSWM) was held at IISc on
working in this direction.
23 and 24 February 2016. The event was jointly organized by the Energy and Wetlands
The conference saw many presentations,
Research Group (EWRG) at the Centre
including posters by students, research scholars
for Ecological Sciences, IISc, Students for
and representatives of various companies and
Development, and the Karnataka Environment
resident welfare associations. They covered
Research Foundation.
topics ranging from data gathering initiatives related to waste management, disposal of
Speakers at the conference emphasized how
construction and debris waste and challenges
individuals can make a difference by more
in dealing with various kinds of waste.
responsible disposal of waste in their own homes, offices and organizations. One could,
ELLEN BROCK
Connect Volume 3 • Issue 2
EECS STUDENTS SYMPOSIUM 2016
The 7th Joint EECS Research Students Symposium was held on 28 and 29 April 2016 at IISc. Participating in the symposium were the Departments
of Computational and Data Sciences (CDS),
Computer Science and Automation (CSA),
Electrical Communication Engineering (ECE),
Electrical Engineering (EE), and Electronic Systems
Engineering (ESE).
The poster session held during the EECS Symposium 2016
"The primary focus of the EECS symposium is to showcase the research work of final year students from these five departments," Dipanjan Gope, one of the members of the organizing committee from ECE, told CONNECT. Over 50 students, both PhD and Master's, made oral and poster presentations of their research work. The event, sponsored by GE, Bosch, and Flipkart, also provided a platform for industry to sample research from these departments at IISc.
The symposium featured four keynote speakers from outside IISc, including Shihab Shamma, University of Maryland—the first occupant of the K Vaidyanathan Distinguished Chair at IISc. Various faculty members from the participating departments also presented their research.
CRESSIDA HAMLET AND PRATEEKSHA VARSHNEY
WORKSHOP ON BIOSAFETY IN LABS
A workshop on Biorisk Preparedness in Laboratory Setting, organized by the National Institute of Virology (NIV), Pune, was held in IISc on 11 April 2016. The goal
of the workshop, led by D T Mourya, Director, NIV, was
to increase awareness about biosafety procedures
and risk assessment in laboratories that handle
Pragya Yadav, Scientist, National Institute of Virology,
demonstrating biosafety training protocols at the workshop
infectious disease pathogens.
Infectious agents are grouped primarily into four categories based on the risk they pose to the individual working with them, and to the community at large. This translates to four biosafety levels (BSL-1, BSL-2, BSL-3 and BSL-4) that are prescribed for handling pathogens from these categories.
To highlight the importance of the mandatory training received by all laboratory personnel handling infectious agents in BSL-3 and BSL-4 facilities, Pragya Yadav, NIV, conducted a hands-on training session at the BSL-3 facility in the Centre for Infectious Disease Research (CIDR), IISc.
MANBEENA CHAWLA
Connect Volume 3 • Issue 2
Manufacturers (SIAM) organized a Design
Workshop on Two-Wheeler Mobility (South
Zone) at the Centre for Product Design and
Manufacturing in IISc on 19-20 March 2016.
SALEEM AHMED
EntorQ 210, an award-winning concept scooter
from TVS Motors, on display during the workshop
A symposium, sponsored by the Centre for
Infectious Disease Research (CIDR), IISc, and
the Infosys Foundation, titled Initiative for
Infectious Disease and Immunology Research
at IISc and Imperial College London (I for I5),
was held on 9-10 March 2016.
MANBEENA CHAWLA
Amit Singh, Assistant Professor, Department of Microbiology and
Cell Biology/Centre for Infectious Disease Research, IISc, speaking
at the symposium
IISc and the Dakshin Foundation, Bangalore, jointly organized an Indo–French workshop
titled Exploring the scope of collaborations in
Marine Biology and Biotechnology between
France and India on 7–9 March 2016 at IISc. The
Centre National de la Recherche Scientifique,
France was one of the agencies with which the
Participants from the workshop relaxing over dinner
Department of Biotechnology, Government of India, partnered in organizing the event.
ADITI JAYARAM
You can read more detailed accounts of these and other events at
http://www.iisc.ac.in/news-events/events/
Connect Volume 3 • Issue 2
LOOK WHO'S TALKING
Some of the important lectures delivered at the IISc in the past few weeks
INSTITUTE COLLOQUIUM: RUDRA PRATAP
"Scientific research alone does not take you where you want to be. How do you overcome the temptation to stop after publishing your paper?" asked Rudra Pratap, Professor and Chairperson, Centre for Nano Science and Engineering (CeNSE), while giving an Institute Colloquium at IISc on 16 March 2016.
In the talk, titled Turning Science into Technology: Narratives of Some Exhilarating Experiences, Pratap addressed the question of how to turn scientific research driven by curiosity into technology and, eventually, innovative products. He did this by drawing on some of the recent research projects from his lab as well as those of his colleagues at CeNSE, which he played a key role in founding in 2010.
Pratap and his team developed a method of etching nano-sized circuits while investigating a phenomenon known as electromigration at the nano-scale—electrons in a conductor moving under the influence of an electric field transfer their momentum to the atoms, resulting in transport of material.
Pratap also spoke about how his colleagues at CeNSE are translating their research into marketable technologies. He gave the example of a diabetes monitoring device developed by Navakanta Bhat (also a professor at CeNSE) and his student Vinay Kumar, which they have commercialized with a start-up called PathShodh.
NITHYANAND RAO
Connect Volume 3 • Issue 2
INSTITUTE COLLOQUIUM: S GOPALAKRISHNAN
S Gopalakrishnan, Professor, Department of Aerospace Engineering, gave an Institute Colloquium on 6 April 2016 titled Wave Propagation in Nanomaterials and Structures. Introducing the subject of nanotechnology, he said that the development of a form of carbon known as carbon nanotube (CNT) in 1991 was a major breakthrough in the field. Compared to steel, CNTs have superior tensile strength—100 times greater—despite being only a sixth as dense. Different forms of CNTs can be used for making various miniature sensors and actuators.
After highlighting the different approaches used in the theoretical modeling of CNTs, Gopalakrishnan spoke about his study of the propagation of mechanical waves in quasicrystals. The structure of a quasicrystal differs from that of crystals in that they are ordered but not periodic. A 3D quasicrystal tiling cannot have translational symmetry in more than two dimensions, unlike crystals which have periodicity in all three dimensions. While crystals can possess only two, three, four, and six-fold rotational symmetries, quasicrystals have other symmetry orders, such as five-fold.
The quasi-periodicity of the quasicrystals leads to two different displacement fields in the material: phonon and phason displacement modes. Gopalakrishnan spoke about his group's work on computing the wavenumber and group-speed of the waves in these two modes in 1, 2 and 3D quasicrystals. His group has also developed characteristic equations to study the variation of wave number and group-speeds in various quasicrystals.
ANUPAM PURWAR
Connect Volume 3 • Issue 2
THE WAXING AND WANING OF
LAC RESEARCH IN IISc
This article traces the early history of lac research in India and the role of researchers in IISc during
Shellac flakes
MEGHA PRAKASH AND MANU RAJAN
A scarlet red wax stick being melted and used
produce lac. The common host trees for lac
to seal envelopes was once a ubiquitous sight
insects include Ber (Zizyphus xylopyrus), Ghont
in post offices. These handcrafted seals were—
(Zizyphus jujuba), Kusum (Schleichera trijuga)
and still are—made from lac.
and Palas (Butea frondosa). The word lac is derived from the Sanskrit laksha, referring to
Lac is the resinous secretion of a specific group
the large number of the tiny insects which
of scale insects. Though there are many species
swarm the trees. It even finds mention in the
of lac insects, the most commonly harvested
epic Mahabharata—Duryodhana, the eldest of
species in India is Kerria lacca. The larvae of
the Kauravas, has a palace called Lakshagraha
these insects pierce through the barks of
built for his cousins, the Pandavas, in which he
particular host trees and suck on their sap to
plans to burn them alive1.
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Lac has been used in India for centuries. Lac
the hands of rural labourers with scanty means
and lac-based products have been used to
and little education. The government believed
make bangles, as a seal, wood finish, cosmetic,
that the farmers neglected the crop when
as dyes for wool and silk, and in the food and
prices were low and were too often tempted
beverages industry. In the early 20th century,
to strip the trees of the brood lac when prices
shellac—the processed form of lac—was used
were high. There were other problems too: the
to make gramophone records, ammunition
use of unscientific methods in the farming of
and electrical goods, and in the paint and
lac, local prejudice, careless manufacturing
varnish industries.
and adulteration. This prompted the British Government in India in 1920 to conduct a
systematic enquiry into the different aspects of lac production and its promotion.
The enquiry was conducted by two government officials, HAF Lindsay and CM
Harlow. Based on their investigations, the
Lindsay-Harlow Report was published in 19213.
It made wide-ranging suggestions, including
Lakhera or Laheri, the traditional artisan community still makes lac
"the establishment of some form of research
bangles in India
organization" that would "work in close touch
with the Forest Department". Based on the
When World War I began, demand for
recommendations, the Indian Lac Association
shellac—particularly in Britain—rose sharply,
for Research (ILAR) was formed in 1921 and
leading to a steep increase in the price of lac
the Indian Lac Research Institute (ILRI) was
in India which had a monopoly in the global
established in Ranchi in 1924.
market with lac exports that were, at the time, valued at Rs. 3 crores2. Because of its use in
Based on the recommendations, the Indian
ammunition, shellac had been accorded the
Lac Association for Research (ILAR) was
formed in 1921 and the Indian Lac Research
status of an industry of strategic importance.
Institute (ILRI) was established in Ranchi in
But the wide fluctuation in the prices of shellac
had exposed it to serious competition from other substitutes. Besides, cultivation was in
Lac Research Gains Ground in IISc
recommendations were being considered for
implementation in 1921, JJ Sudborough, the
first head of the Department of General and
Organic Chemistry in IISc, and HE Watson,
a professor in the same department, had
been researching the purification of lac
Lac accumulating on the bark of a host plant
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and distillation of sandalwood oil. Another
produced by the lac insect, and studied the
researcher from IISc who worked on lac was
extraction of lac-dye. Two other researchers,
Gilbert Fowler, a sanitary chemist and professor
CR Somayajulu and M Rangaswami, also
in the Department of Applied Chemistry, who
contributed to the study of host plants. Later
had earlier obtained a patent4 for inventing
entrants into lac research included BH Krishna,
an improved process for obtaining pure
who studied the nutrition of the lac insect,
shellac from stick-lac (a stick with loads of
and MA Qadir who perfected a technique for
eggs covered in lac). At IISc, Fowler worked on
bleaching lac and the utilization of lac dust.
lac with S Mahdihassan and M Sreenivasaya,
deputed to the Institute by the Governments of Hyderabad and Mysore respectively. The three
of them jointly published a series of papers
experiments, field investigations on lac were
titled "Contributions to the Scientific Study of
carried out in Lal Bagh, a farm in Hebbal and
the Lac Industry" in 10 parts in the Journal of
in the campus of IISc. The main experimental
the Indian Institute of Science in 1924.
site, however, was a plantation with jalari trees adjoining the village of Doraisanipalya near
Mahdihassan, an entomologist, studied the
Bannerghatta, 6 miles south of Bangalore.
anatomy and physiology of the lac insect.
Here, records of the number of broods of
He succeeded in identifying the special
lac insects per year and the outturn of stick-
glands that produced the various substances
lac per crop were meticulously maintained.
found in stick-lac, including wax and resins.
Facilities were created in the Institute campus
Mahdihassan also studied the sex-ratio (which
for the technical preparation of seed-lac and
varied widely under different conditions) of the
lac-dye—a set of concrete tanks that were
insect and found a way to determine the sex of
originally constructed for the treatment of
the larva at an early stage in its development.
effluent from the fermentation process for
Besides his own research, he translated an
production of acetone, and located adjoining
important monograph by B Hautefeuille, Lac
the Department of Applied Chemistry, were
and its Industrial Treatment in Indo-China, from
modified to serve as washing tanks for stick-
French to English.
lac. The services provided by the Governments of Mysore and Hyderabad also facilitated lac
Sreenivasaya, on the other hand, carried out
research in the Institute: Leslie C Coleman, the
investigations to determine how the food of
Director of the Department of Agriculture of
the insect was converted into lac. Mahdihassan
Mysore and a member of the Governing Council
and Sreenivasaya were assisted by RD Rege and
of IISc, offered the facilities in his department
DN Gupta, students in the newly established
for the benefit of the Institute's researchers;
Department of Biochemistry; Rege worked
the Government of Hyderabad made available
on the chemical composition and physical
two artists who produced a large number of
characteristics of the host plants, while Gupta
coloured drawings of characteristic lac cell
investigated the chemistry of resins and waxes
formations and parasites.
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Interaction with Industry
instituted in his honour for the best PhD thesis
Lac researchers in the Institute interacted with
from the Department of Microbiology and Cell
local industries for the preparation of lac-based
products. The Channapatna Lacquer Works collaborated with IISc for the manufacture
The setting up of ILRI in Ranchi resulted in a
of lacquer, a glossy material used for surface
number of researchers from IISc moving there
coating of wood. Sreenivasaya perfected a
Though the strategic significance of lac waned
method to produce commercial crude lac-
over time, it continued to be an important
dye which also resulted in the making of a
commodity. Lac harvesting still impacts the
certain kind of French Polish, a wood finish
livelihood of a sizable section of the tribal
that became prized by connoisseurs of
population of Jharkhand, Chhattisgarh,
woodworking. This polish was tested by the
Madhya Pradesh and Odisha. These lac farmers
Mysore Railways successfully; after the testing,
are engaged in the cultivation and processing
its large scale production by a private firm was
of lac, and interested in new ways of combating
seriously considered. The Institute staff also
pests and increasing production. The early
wrote several articles on lac products in the 2nd
pioneering work on lac by researchers from
edition of the Munitions Board Handbook (a
IISc was built upon in successive decades by
handbook on Industrial Chemistry).
ILRI. In 2007, the research areas of ILRI were broadened, and it was renamed as the Indian
Downturn in IISc
Institute of Natural Resins and Gums.
The setting up of ILRI in Ranchi resulted in a number of researchers from IISc moving there.
The content of the article is based primarily on
ILRI's first Director was Dorothy Norris, who
information available in the Annual Reports of IISc
earlier had a brief stint with the Department of
(1916-17; 1918-19; 1919-20; 1920-21; 1922-23; 1923-
Applied Chemistry at IISc, where she worked
24; 1924-25; 1926-27; 1928-29; 1930-31; 1932-33)
on fermentation of alcohol, lactic acid and acetic acid. DN Gupta and M Rangaswami
Other references:
were appointed as Chemical Assistants. M
1. https://en.wikipedia.org/wiki/Lakshagraha
Venugopalan, whose work was focused on
2. General Introduction by Gilbert Fowler,
the washing and bleaching of lac, and S
Contributions to the scientific study of the lac industry, Journal of the Indian Institute of Science,
Ranganathan, a student in the Department
Vol. 7, Part VII, p. 97-103
of Biochemistry who had worked with
3. Report on Lac and Shellac, HAF Lindsay and LM
Sreenivasaya, joined ILRI as Field Chemists.
Harlow, The Indian Forest Records, Vol. viii, Part I,
Sreenivasaya, though, opted to continue in
IISc. He was appointed as a lecturer in the
4. Process for obtaining pure shellac from stick-lac or
Institute in 1941 and became the head of
the like, Patent No. US 975224 A, Gilbert J. Fowler (1910); www.google.com/patents/US975224
the Fermentation Technology Unit in the
5. Souvenir: A Glimpse of the 75 Years (1940-2015),
Department of Pure and Applied Chemistry a
Department of Molecular Biology and Cell Biology,
year later. An annual memorial award has been
Connect Volume 3 • Issue 2
AND THE WINNERS ARE…
Members of the IISc community who were recently honoured with awards
Shalabh Bhatnagar
Professor, Computer
Professor, Centre for
Science and Automation,
Neuroscience, Shanti
Prof. Satish Dhawan
Swarup Bhatnagar Prize
Young Engineer Award,
Government of Karnataka
Gadadhar Misra
Professor, Department of
Professor, Department
Inorganic and Physical
of Mathematics,
Chemistry, Indian
Mathematician of the
Society of Chemists and
year, Ponnala Foundation
Biologists Award for
jointly with NIT Warangal
Aditya Garai
Student, Department of
Professor, Department of
Inorganic and Physical
Electrical Communication
Chemistry, Gandhi
Engineering, IETE
Young Technological
SVC Aiya Award for
Excellence in Telecom
Education & Osmania
University College of Engineering
Distinguished Alumnus Award
Sai Siva Gorthi
Assistant Professor,
G Narayanan
Department of
Associate Professor,
Instrumentation and
Department of Electrical
Applied Physics, ISOI
Engineering, Prof. Satish
Young Scientist/
Dhawan Young Engineer
Engineer Award,
Award, Government of
Instrumentation Society of India
Diptiman Sen
Manju Bansal
Professor, Centre for High
Professor, Molecular
Energy Physics, JC Bose
Biophysics Unit, JC Bose
Connect Volume 3 • Issue 2
Campus Critters
Connect Volume 3 • Issue 2
Department of Mathematics
Connect Volume 3 • Issue 2
Source: http://apc.iisc.ernet.in/newsletter/pdf/issue22016.pdf
Gruppo Italiano per la Medicina Basata sulle Evidenze Le opportunità di un linguaggio comune 2a ed. Evidence-Based Medicine Italian Group Como, 21-22 maggio 2004 Sezione di Como Workshop Clinici Interattivi (1) La gestione del paziente con emicrania in medicina generale: verso l'integrazione
Minnesota Chapter of the American Academy of Pediatrics Pediatric Abstract and Poster Competition Hilton Hotel- MOA/MSP Bloomington, MN Medical Student Roma Patel What does that lab really mean? MSV Matthew Armfield, Introduction: Ovarian masses in the pre-pubertal population are concerning